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WCBS 880AM Interview with Dr. Daniel Kellner on Enlarged Prostates

November 08, 2021
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  • 00:15my name is Doctor Daniel Kellner.
  • 00:17I'm a urologist at Yale Medicine,
  • 00:19which is a multi specialty group in
  • 00:21the old School of Medicine and I'm a
  • 00:23general urologist, but I have a special
  • 00:25interest in BPH in men's health.
  • 00:27I practice in New Haven,
  • 00:29CT, but I also have offices.
  • 00:31In Madison, CT and Hamden, CT
  • 00:33we're talking this morning with Doctor
  • 00:35Daniel Kellner of Yale Medicine,
  • 00:37and you are a urologist and you
  • 00:39have an emphasis on men's health.
  • 00:41Is it a struggle?
  • 00:42First of all, to get guys to see
  • 00:45a urologist in the first place,
  • 00:47I think typically men are are less
  • 00:49likely to want to go to the doctor,
  • 00:51but unfortunately you
  • 00:52can't avoid your bladder.
  • 00:53And many times people are certainly
  • 00:55at their very aggravated by their
  • 00:57situation and so they'll end up making an
  • 00:59appointment because if you ignore problem,
  • 01:01it doesn't really go away.
  • 01:02Or sometimes I have a friend who
  • 01:04had a similar situation and kind
  • 01:05of clue them in that there is help.
  • 01:07So many men who come to me.
  • 01:08They've come to me because they are friends,
  • 01:10but it's similar experience or coworker
  • 01:12would have similar experience and then
  • 01:14obviously they're prompted sometimes by
  • 01:15their significant other to to come in.
  • 01:17No girlfriend, wife,
  • 01:18partner because someone else is
  • 01:19recognizing that they're having
  • 01:21difficulty with what their bladder.
  • 01:22Let's go over the symptoms and how severe
  • 01:25do the symptoms have to get before you
  • 01:28consider some of the procedures that
  • 01:30were going to talk about today? When
  • 01:33men have BPH, the prostate is
  • 01:35typically the size of a walnut,
  • 01:38and it can continue to grow,
  • 01:40and it could obstruct the urethra.
  • 01:41And that's the tube empties the
  • 01:43bladder and prostate doesn't have
  • 01:44to be big to constrict that too,
  • 01:46and symptoms could be increased
  • 01:48frequency to urinate,
  • 01:49increased urgency to urinate,
  • 01:50a slower stream or the stream
  • 01:52could be hesitant or intermittent,
  • 01:54or there may be more getting
  • 01:55up at night to urinate.
  • 01:56These things could affect the quality
  • 01:58of life, so in in other words,
  • 02:00sometimes men will be distracted at work.
  • 02:02They'll be thinking about.
  • 02:03You know where bathroom is or if
  • 02:04they go shopping or they're driving.
  • 02:05They're always kind of aware
  • 02:07where a bathroom is,
  • 02:08or to make sure that they
  • 02:09urinate before they go anywhere,
  • 02:10and so the symptoms could be quite subtle,
  • 02:12but there could be a more
  • 02:14serious underlying problem,
  • 02:15because men could actually be
  • 02:17developing urinary retention,
  • 02:18and they're aware of the symptoms are having,
  • 02:20but they're not aware that
  • 02:21they're retaining urine,
  • 02:22and when that urine is
  • 02:23retained in the bladder,
  • 02:24they could actually start to cause
  • 02:26problems with the buyer with the
  • 02:27bladder will start to retain urine,
  • 02:29and the buyer could get quite large,
  • 02:31and that pressure to even
  • 02:32back up to the kidneys and.
  • 02:33Does kidney damage and it's a
  • 02:34bar is not emptying properly.
  • 02:36It can lead to other problems
  • 02:37such as urinary tract infections,
  • 02:39bladder stones,
  • 02:40other things could be a problem,
  • 02:42so men may be aware of subtle symptoms,
  • 02:44but they're not going to necessarily
  • 02:45be aware that there is a more
  • 02:47ominous problem that may be
  • 02:48happening that they're not aware of.
  • 02:49So where do you come in and
  • 02:51how do you fix these problems
  • 02:54when it comes to me and they have urinary
  • 02:56problems and the first thing I do is
  • 02:58simply do a history and physical and try
  • 03:00to assess the degree of their problems.
  • 03:01We have a questionnaire we often.
  • 03:03Use quality anyway.
  • 03:04Symptoms for the American
  • 03:06neurologic symptoms score,
  • 03:07which is a series of questions and
  • 03:09it often kind of gauge how severe
  • 03:11a patient or a man symptoms are.
  • 03:13And often we could categorize them as
  • 03:15kind of mild, moderate or severe symptoms.
  • 03:16We also have ways of measuring
  • 03:18the bladder to see if it empties.
  • 03:20We call that a post void residual,
  • 03:22and then we also assess things that
  • 03:24may be contributing to the area.
  • 03:25Symptoms such as excessive caffeine intake,
  • 03:28alcohol intake,
  • 03:29certain medications that are
  • 03:30prescribed such as diuretics which
  • 03:32could cause urinary symptoms so.
  • 03:33That's how we initially evaluate a man
  • 03:35what has to happen for you to decide
  • 03:38to go to the euro lift? Let's say
  • 03:41when a man has difficulty with urinating
  • 03:43and first thing we do is lifestyle.
  • 03:44Modifications typically will try men
  • 03:46on medications and there are different
  • 03:48medications that relax the prostate,
  • 03:50make it easier to pass the urine.
  • 03:53If a man is not having a
  • 03:54good response to medications,
  • 03:56side effects from medications,
  • 03:57or simply does not want to take medicine,
  • 04:00we could think of alternative
  • 04:01options such as the euro lift.
  • 04:03Now the euro lift.
  • 04:04Is a procedure that is done
  • 04:05where you put an implant into the
  • 04:07prostate and it holds the prostate
  • 04:09tissue in an unobstructed way.
  • 04:11Basically opening the channel
  • 04:12and making it easier to urinate.
  • 04:14Now one of the appeals of the euro
  • 04:16lift is it also could be done right in
  • 04:18the office with a local anesthetic,
  • 04:20and there is a relatively quick
  • 04:22recovery and significant improvement
  • 04:24in urinary symptoms,
  • 04:26but it doesn't fix the enlarged prostate.
  • 04:29Is the prostate still enlarged
  • 04:31so when you do that, you roll it?
  • 04:33You're not removing any tissue.
  • 04:34You're not burning any tissue.
  • 04:35Nothing is being removed.
  • 04:36You're simply taking that issue
  • 04:38that's obstructing and by putting
  • 04:39these implants and you move the
  • 04:41tissue into unobstructed way.
  • 04:42I mean, you could think of something like a,
  • 04:44you know, like a hose.
  • 04:45If you if you basically have
  • 04:46your thumb partly over host,
  • 04:48it really changes the flow of the liquid,
  • 04:50right? I'm removing moving
  • 04:51your thumb out of the way.
  • 04:53The flow is going to change a lot,
  • 04:54and so with the Europe is similar.
  • 04:55If you basically move that tissue
  • 04:57out of the way and you don't
  • 04:58necessarily move is very far.
  • 04:59The air flow is going to be much better,
  • 05:01and when that happens,
  • 05:02then typically the other symptoms.
  • 05:04Starts to get better too,
  • 05:05such as the frequency of urinating
  • 05:07urgency to urinate so that one of the
  • 05:09appeals of the euro lift for many men
  • 05:11as well is there are no documented
  • 05:13sexual side effects because many of
  • 05:15the other surgeries that we do or
  • 05:17some of the medications that we give
  • 05:19sometimes interfere with the ability
  • 05:20to ejaculate or could sometimes
  • 05:22even cause problems with erections.
  • 05:24So the euro it has really no
  • 05:26documented sexual side effects,
  • 05:27so that is very appealing to many men.
  • 05:29Does it return a guide to normal?
  • 05:31Not maybe to his 20s? But does it?
  • 05:34Return him to a normal urinary flow, then
  • 05:37at times there is a very very remarkable
  • 05:40improvement with the euro lift.
  • 05:42I mean, I think it is very important
  • 05:43that a managed properly selected
  • 05:44there are certain anatomy's that are
  • 05:46very good for your lip procedure.
  • 05:48I think there are other anatomy
  • 05:49is where a person really is,
  • 05:50not a good candidate for the airlift.
  • 05:52And if they're not a good
  • 05:53candidate for their lists,
  • 05:53the fortunate thing is we actually have
  • 05:55many other procedures that could be done
  • 05:56which could help them out by anatomy.
  • 05:58What do you mean?
  • 05:59I mean, the prostate anatomy,
  • 06:00the size of the prostate,
  • 06:02and the shape of the prostate has to be.
  • 06:04Determined there are certain
  • 06:05shapes of the prostate,
  • 06:07just basically the where the tissue
  • 06:08is located in how it's constricting,
  • 06:10which could determine if the
  • 06:11airlift is a good procedure or not.
  • 06:13So I think it's really up to the
  • 06:15experience of the urologist to
  • 06:16kind of distinguish who is a good
  • 06:18candidate for euro lift and who isn't.
  • 06:19It's not a good procedure across
  • 06:21the board for every man,
  • 06:22so I think every man has to be
  • 06:23evaluated often times that we have
  • 06:25to do what's called a cystoscopy,
  • 06:26where we look directly inside
  • 06:27the prostate at that issue.
  • 06:29And then we could figure out if the person
  • 06:31is a good candidate for the euro lift.
  • 06:32Do you usually need to do a euro lift?
  • 06:35Again, down the road,
  • 06:36or is it once and done? Usually
  • 06:39the euro lift has very very good durability.
  • 06:42When it was approved by the FDA,
  • 06:44there was a trial club,
  • 06:44a lift trial which looked at five year
  • 06:47follow up in the retreatment rate.
  • 06:48The surgical retreatment rate
  • 06:50for euro lift is about 13 to 14%.
  • 06:53So most men at five years are going to be
  • 06:56OK with that or after having the airlift.
  • 06:58But there will be a certain percentage
  • 07:00of men who may need to go on to
  • 07:01have either another euro lift or a
  • 07:03different procedure to help them.
  • 07:04What is? Recovery like for euro lift.
  • 07:07Most men after euro lift of
  • 07:09experienced some irritative urinary
  • 07:11symptoms so they may have some
  • 07:12urgency or frequency to urinate.
  • 07:14Some burning with urination,
  • 07:15some blood in the urine and this usually
  • 07:18goes on for a few days and then he thinks
  • 07:20they kind of get better over a few weeks.
  • 07:22Or maybe maybe mild symptoms and
  • 07:24over the course of several weeks.
  • 07:26Then you start to see the
  • 07:28improvement in the urination.
  • 07:29There are other procedures though
  • 07:31that address BPH and you want to talk
  • 07:34about one of them today. That you do
  • 07:36right? So I'd like to talk about
  • 07:38a procedure called the whole LIP,
  • 07:40which is holmium laser enucleation
  • 07:42or prostate, and this is a very
  • 07:44unique procedure at Yale Medicine.
  • 07:46We are the only group in Connecticut
  • 07:48that actually performs this procedure.
  • 07:50Surgical technique which is minimally
  • 07:52invasive where you go inside the
  • 07:53prostate with a scope and you're
  • 07:55able to basically peel out the
  • 07:57inside of the prostate like you're
  • 07:58peeling out the inside of an orange.
  • 08:00And the nice thing about this
  • 08:02procedure is it's really complete.
  • 08:04Removal of the inside of the prostate.
  • 08:06And there's very little bleeding,
  • 08:07similar to if you're in the right.
  • 08:09If you're peeling an orange
  • 08:09in here in the right plane,
  • 08:10there's very little juice.
  • 08:12Well, just think of that juice as blood,
  • 08:13so when you get into the right plane,
  • 08:15you could basically peel out the inside
  • 08:17of the prostate so it's really complete.
  • 08:19Removal of the inside of the prostate,
  • 08:20and then we use an instrument
  • 08:22called the morsel later,
  • 08:22which removes the tissue.
  • 08:23So there's no in stations,
  • 08:24and with this procedure you
  • 08:26can treat any size prostate,
  • 08:28so for very very very large prostates
  • 08:31manner have very few options.
  • 08:32Be able to treat them,
  • 08:34and they often have to consider
  • 08:35an open surgical.
  • 08:36Approach,
  • 08:36which is very morbid and it requires
  • 08:39several days in the hospital.
  • 08:41Potentially a lot of bleeding with
  • 08:42the procedure called the whole app.
  • 08:44We can do these surgeries without
  • 08:46any incisions,
  • 08:46and most of our patients go home
  • 08:48the same day and actually is.
  • 08:49And also we have very little pain.
  • 08:51Actually I don't even prescribe pain
  • 08:53medication with this procedure,
  • 08:54'cause men really don't complain
  • 08:55of pain with the procedure.
  • 08:56Now the way you describe it,
  • 08:57I would think that it would rely
  • 08:59really on the skill of the surgeon
  • 09:02and the artistry of the surgeon.
  • 09:04It's a difficult surgery
  • 09:05to learn if there is.
  • 09:06Certainly a learning curve,
  • 09:07and I think you need to be a
  • 09:10dedicated surgeon who really
  • 09:11wants to focus on this procedure.
  • 09:12This is not a procedure that's
  • 09:15done casually by any urologist,
  • 09:17so for someone who's doing a whole,
  • 09:18if you really kind of have to be
  • 09:20dedicated to the art of doing
  • 09:21this procedure so we have a
  • 09:23very successful program at Yale,
  • 09:24we've been doing them since 2019 and
  • 09:26actually we have patients were coming
  • 09:28from all over Connecticut and even
  • 09:30outside states such as Massachusetts,
  • 09:32Rhode Island, New York,
  • 09:33because they hear about this procedure
  • 09:35and and once they find out about it,
  • 09:36they have a lot of interest.
  • 09:37What is the benefit of the
  • 09:40whole up over the euro lift
  • 09:42so the euro lift is really good for
  • 09:44patients who have prostates are
  • 09:46kind of on the smaller side that the
  • 09:48original approval of the airlift was
  • 09:50for properties from 30 to 80 grams.
  • 09:52And now it's just been extended from 30
  • 09:55to 100 grams with the whole of procedure.
  • 09:57You can do any size prostate you
  • 09:59can do prostate better,
  • 10:00even several 100 grams and the
  • 10:02whole app is really good for any
  • 10:04prostate versus the euro lift is
  • 10:06going to be good on select prostate.
  • 10:08Based on the anatomy
  • 10:09and what is the recovery like for Jolla
  • 10:12so most patients will go home
  • 10:14the same day after the whole app.
  • 10:16They live far away.
  • 10:17Sometimes will keep them overnight and
  • 10:19usually we keep a catheter in for a day
  • 10:21or two after the catheter comes out,
  • 10:23so they should not do any heavy lifting
  • 10:25or straining this activity for about
  • 10:26two or three weeks so they can drive.
  • 10:28They can walk, they can shower,
  • 10:30and after two or three weeks they could
  • 10:32start to do normal activity again.
  • 10:34I noticed that there are ads
  • 10:36online and on television.
  • 10:38And on radio for some of these procedures
  • 10:41that you never used to see before,
  • 10:43I guess it was taboo.
  • 10:44Is the taboo around this topic lifting?
  • 10:48Do you think?
  • 10:49Or why are we talking about it more
  • 10:51and seeing more of this in your view?
  • 10:53Well, I think that the reason we're
  • 10:55seeing a lot more of this on TV and
  • 10:57other places this is marketing.
  • 10:59There is a business aspect terms of
  • 11:01you know products that are being used.
  • 11:03But it also comes with good intention.
  • 11:05I mean there is a huge huge need for men.
  • 11:08We're having difficulty
  • 11:10urinating who need care,
  • 11:11and so I think it is good that men are
  • 11:13being made aware of different options.
  • 11:15Making this conversation come to life.
  • 11:18Universe is something that
  • 11:19you just don't talk about.
  • 11:20I mean, I think some men they
  • 11:21just accept that part of aging
  • 11:23is having difficulty urinating
  • 11:25getting up many times at night.
  • 11:26You know,
  • 11:27not being able to sit through a movie
  • 11:28without having to get up a few times and
  • 11:30it really doesn't have to be that way there.
  • 11:32There are treatments that are available
  • 11:33and it's just a matter of kind of
  • 11:35looking for those treatments and
  • 11:36finding out what's right for you.
  • 11:37Must be a lot of satisfaction.
  • 11:39Doing what you do,
  • 11:40it's very satisfying,
  • 11:41so my focus is really meant self.
  • 11:43But really my my passion is treating BPH.
  • 11:46It's very very black and white.
  • 11:47I mean when you have someone who
  • 11:48can't urinate and they may have
  • 11:50a catheter end and then you can
  • 11:51do a procedure and then then the
  • 11:52next day they're able to urinate
  • 11:54like they're ten years old again.
  • 11:55I mean, it's a very, very satisfying,
  • 11:57so there's no school of delay gratification.
  • 12:00I mean, you get some gratification
  • 12:01very quickly when you treat BPH,
  • 12:03able to help someone urinate.
  • 12:05And I think I think I make a lot of
  • 12:07lifelong friends by doing this procedure,
  • 12:09so it it's.
  • 12:09One of the things that I really enjoy,
  • 12:11well, I can tell your passion
  • 12:13really comes through anything else
  • 12:15that you want to add on either
  • 12:16the euro lift or the whole lip. I
  • 12:18think there are many
  • 12:20different options for men.
  • 12:21I think it's important that
  • 12:23basically they make an appointment.
  • 12:24You have to see the urologist to
  • 12:25be able to go over the different
  • 12:27options that are available.
  • 12:28I think men are pretty savvy these days.
  • 12:31What they could learn on the Internet?
  • 12:32Many of them come in with some
  • 12:34knowledge of what's available and
  • 12:35then when they come in I could kind
  • 12:37of tailor the right approach to.
  • 12:39The person based on what really what
  • 12:41their desire is, is their number.
  • 12:42One desire to preserve sexual function,
  • 12:44but they want to urinate better
  • 12:45or is their desire to have one
  • 12:47procedure where they're going to
  • 12:48have the best urinating or will
  • 12:50ever be able to achieve and never
  • 12:51need another surgery again.
  • 12:53So we can kind of tell her what
  • 12:54the the treatment is to the
  • 12:56patient and what their desire is.
  • 12:58Well you've given us a lot
  • 13:00of information and I want to
  • 13:01thank you for taking the time.
  • 13:03No thank you.
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