Research Programs

Yale researchers have introduced countless medical and health advances over the last century, including the first success with antibiotics in the United States and the first use of chemotherapy to treat cancer. University scientists have been responsible for the identification of Lyme disease and the discovery of genes responsible for high blood pressure, osteoporosis, dyslexia, and Tourette's syndrome, among other disorders. Early work on the artificial heart and the creation of the first insulin pump took place at Yale, as did seminal discoveries about how the cell and its components function at the molecular level. Today, research activities take place in a wide range of departments, programs, and centers.

As of fiscal year 2013 Yale research has had 1,815 awards totaling $510.4 million, 416 U.S. and 704 worldwide active patents for Yale inventions, and 58 Yale-founded biotech companies.

The School of Medicine has extraordinary strength in the basic sciences and consistently ranks in the top handful of medical schools receiving funding from the National Institutes of Health.

Productive and prominent programs in basic, clinical, and translational research are fundamental to the development of clinical excellence and our academic mission. Our surgeons actively conduct leading-edge studies that significantly contribute to the science of cardiac health and care.

Time and again, findings from our surgeons have been published in leading and peer-reviewed medical journals and have been recognized with prestigious awards and achievements.

Funding for research projects have included support from National Institutes of Health and the National Science Foundation. 

Led by our faculty surgeons, research programs also include involvement by Yale University medical students, residents, and pre– and postdoctoral fellows.

Current research programs include:

  • Aortic Aneurysmal Disease Research - John Elefteriades, MD
  • Congenital Heart Disease Surgical Treatments and Cardiovascular Surgery in Low Birth Weight Neonates Research - Gary Kopf, MD 
  • "Cooling Catheter" for Protecting the Spinal Cord From Ischemic Injury During Aortic Surgery - John Elefteriades, MD
  • New Mechanical Cardiac Support Devices - Abeel Mangi, MD
  • Surgical Treatment of Congenital Heart Disease and Cardiovascular Surgery in Low Birth Weight Neonates Research - Gary Kopf, MD 
  • Trans-catheter therapies for heart valve disorders - Abeel Mangi, MD
  • Vascular Biology and Transplantation Immunology - George Tellides, MD, PhD
  • Wireless Energy Transfer - Pramod Bonde, MD