Skip to Main Content

Martin Schwartz, PhD

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Biomedical Engineering and of Cell Biology



Martin Schwartz earned a BA in chemistry from New College in Sarasota FL and a PhD in physical chemistry from Stanford, where he worked in Harden McConnell’s lab on biophysics of phospholipid membranes.He then did postdoctoral research in biology at MIT in the laboratory of Richard Hynes where he studied interactions of fibronectin with cells and other proteins. He was on the faculty at Harvard Medical School, Scripps Research Institute and the University of Virginia prior to moving to Yale in 2011. Starting in the 1980’s, his lab was among the first to report that integrin mediated adhesion could regulate signaling pathways in cells;that integrin-mediated adhesion promotes cell survival, that integrins synergize with growth factor receptors to activate growth signaling pathways and that integrins regulate Rho family GTPases. His lab has also elucidated mechanotransduction pathways by which endothelial cells respond to fluid shear stress to activate inflammatory pathways linked to atherosclerosis. His current research program combines studies using biophysical, cellular and animal approaches to important questions about integrin signaling, mechanotransduction and disease in the vascular system.

Education & Training

  • Postdoctoral fellow
    MIT (1982)
  • PhD
    Stanford University (1979)
  • BA
    New College of the University South Florida (1975)

Honors & Recognition

AwardAwarding OrganizationDate
Greenblatt Distinguished LectureMedical College of Georgia2021
Bolie LectureUniversity of Colorado2019
Fellow of the American Society for Cell BiologyAmerican Society for Cell Biology2017
Fellow of the American Association for Advancement of ScienceAmerican Association for Advancement of Science2016
Harold F. Dvorak Plenary LectureHarvard Medical School2013
Andrew P. Somlyo Honorary LecturePennsylvania Muscle Institute, University of Pennsylvania2013
Robert W. Berliner Professor of MedicineYale School of Medicine2012
Hayashi Lecturer, Woods Hole MBL Physiology CourseMarine Biology Laboratory2009
James O. Davis LectureshipUniversity of Missouri2009

Professional Service

Gordon Research Conference, Signaling by Cell Adhesion ReceptorChairperson2012
Frontiers in Cell Migration & MechanotransductionChairperson2011
Gordon Research Conference, Vascular Cell BiologyChairperson2011
Mechanotransduction in Physiology and DiseaseChairperson2009
Biochemical Journal (2006-2008)Associate Editor2006 - 2015
Keystone conference on Signaling by Integrins and Growth Factor ReceptorsChairperson1998
Keystone conference on Integrins and Signaling Events in Cell Biology and DiseaseChairperson1996
Matrix Biology (1997-2012)Board Member
Journal of Cell Biology (2001-present)Associate Editor
Journal of Cell Science (2006-present)Board Member

Departments & Organizations