Jeffery Kocsis, PhD
Professor of Neurology and of NeuroscienceDownloadHi-Res Photo
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Appointments
Neurology
Primary
Neuroscience
Secondary
Additional Titles
Director , Postdoctoral Studies
Associate Director, Yale Center for Neuroscience and Regeneration Research
Senior Medical Research Career Scientist, Department of Veterans Affairs
Contact Info
Appointments
Neurology
Primary
Neuroscience
Secondary
Additional Titles
Director , Postdoctoral Studies
Associate Director, Yale Center for Neuroscience and Regeneration Research
Senior Medical Research Career Scientist, Department of Veterans Affairs
Contact Info
Appointments
Neurology
Primary
Neuroscience
Secondary
Additional Titles
Director , Postdoctoral Studies
Associate Director, Yale Center for Neuroscience and Regeneration Research
Senior Medical Research Career Scientist, Department of Veterans Affairs
Contact Info
About
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Titles
Professor of Neurology and of Neuroscience
Director , Postdoctoral Studies; Associate Director, Yale Center for Neuroscience and Regeneration Research; Senior Medical Research Career Scientist, Department of Veterans Affairs
Appointments
Neurology
ProfessorPrimaryNeuroscience
ProfessorSecondary
Other Departments & Organizations
Education & Training
- PhD
- Wayne State University (1976)
Research
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Overview
Medical Research Interests
Cell Transplantation; Central Nervous System; Ion Channels; Nerve Regeneration; Neurology; Neurosciences; Spinal Cord; Spinal Cord Injuries; Veterans
ORCID
0000-0002-3780-7719
Research at a Glance
Yale Co-Authors
Frequent collaborators of Jeffery Kocsis's published research.
Publications Timeline
A big-picture view of Jeffery Kocsis's research output by year.
Research Interests
Research topics Jeffery Kocsis is interested in exploring.
Stephen Waxman, MD, PhD
Masanori Sasaki, MD, PhD
Karen L Lankford, PhD
Osamu Honmou, MD, PhD
Masahito Nakazaki
Former YSMStephen Strittmatter, MD, PhD, AB
144Publications
7,953Citations
Nerve Regeneration
Spinal Cord
Spinal Cord Injuries
Ion Channels
Cell Transplantation
Central Nervous System
Publications
2026
Mesenchymal stromal/stem cell-derived extracellular vesicles in brain disorders: mechanisms of repair and recovery
Nakazaki M, Lankford K, Ukai R, Hirota R, Oka S, Sasaki M, Kocsis J, Honmou O. Mesenchymal stromal/stem cell-derived extracellular vesicles in brain disorders: mechanisms of repair and recovery. Frontiers In Cellular Neuroscience 2026, 20: 1819046. PMID: 42179845, PMCID: PMC13193808, DOI: 10.3389/fncel.2026.1819046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricThe Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle–Mediated Tissue Repair After Spinal Cord Injury
Nakazaki M, Lankford K, Yokoyama T, Ukai R, Hirota R, Oka S, Sasaki M, Kocsis J, Honmou O. The Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle–Mediated Tissue Repair After Spinal Cord Injury. Frontiers In Bioscience-Landmark 2026, 31: 47612. PMID: 42052826, DOI: 10.31083/fbl47612.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsContinuous intravenous infusion of human mesenchymal stromal cell-derived small extracellular vesicles in spinal cord injured rat modulates extracellular matrix and has greater therapeutic efficacy than multiple single injections
Nakazaki M, Lankford K, Toyoshima M, Tanaka Y, Sumida T, Kocsis J. Continuous intravenous infusion of human mesenchymal stromal cell-derived small extracellular vesicles in spinal cord injured rat modulates extracellular matrix and has greater therapeutic efficacy than multiple single injections. Neurotherapeutics 2026, 23: e00892. PMID: 41894999, PMCID: PMC13054005, DOI: 10.1016/j.neurot.2026.e00892.Peer-Reviewed Original ResearchCitationsAltmetricIntranasal administration of human mesenchymal stromal cell-derived small extracellular vesicles delays disease progression in the SOD1(G93A) mouse model
Hirota R, Lankford K, Nakazaki M, Toyoshima M, Kocsis J. Intranasal administration of human mesenchymal stromal cell-derived small extracellular vesicles delays disease progression in the SOD1(G93A) mouse model. Molecular Brain 2026, 19: 22. PMID: 41776544, PMCID: PMC13063686, DOI: 10.1186/s13041-026-01288-0.Peer-Reviewed Original ResearchCitationsAltmetric
2025
Mesenchymal stem cells reverse disease-specific abnormalities in nociceptive regions of the brain
Fukushi R, Sasaki M, Obara H, Kurihara K, Hirota R, Morita T, Teramoto A, Yamashita T, Tan A, Waxman S, Kocsis J, Honmou O. Mesenchymal stem cells reverse disease-specific abnormalities in nociceptive regions of the brain. Brain Communications 2025, 8: fcaf494. PMID: 41509715, PMCID: PMC12776362, DOI: 10.1093/braincomms/fcaf494.Peer-Reviewed Original ResearchAltmetricTherapeutic Efficacy of Mesenchymal Stem Cells in Modulating Oxidative Stress in Puromycin-Induced Nephropathy
Iizuka Y, Sasaki M, Terada K, Sakai T, Nagaoka Y, Fukumura S, Kocsis J, Tsugawa T, Honmou O. Therapeutic Efficacy of Mesenchymal Stem Cells in Modulating Oxidative Stress in Puromycin-Induced Nephropathy. Pathophysiology 2025, 32: 19. PMID: 40407599, PMCID: PMC12101160, DOI: 10.3390/pathophysiology32020019.Peer-Reviewed Original ResearchCitationsIntravenous infusion of mesenchymal stem cells increased axonal signal intensity in the rubrospinal tract in spinal cord injury
Hirota R, Sasaki M, Teramoto A, Yamashita T, Kocsis J, Honmou O. Intravenous infusion of mesenchymal stem cells increased axonal signal intensity in the rubrospinal tract in spinal cord injury. Molecular Brain 2025, 18: 35. PMID: 40241097, PMCID: PMC12004759, DOI: 10.1186/s13041-025-01210-0.Peer-Reviewed Original ResearchCitationsAltmetric
2024
Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood–Spinal Cord Barrier Repair Following Spinal Cord Injury
Nakazaki M, Yokoyama T, Lankford K, Hirota R, Kocsis J, Honmou O. Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood–Spinal Cord Barrier Repair Following Spinal Cord Injury. International Journal Of Molecular Sciences 2024, 25: 13460. PMID: 39769223, PMCID: PMC11677717, DOI: 10.3390/ijms252413460.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsMultiple intravenous infusions versus a single infusion of mesenchymal stem cells in a rat model of cerebral ischemia.
Yokoyama T, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Ukai R, Oka S, Kocsis J, Honmou O. Multiple intravenous infusions versus a single infusion of mesenchymal stem cells in a rat model of cerebral ischemia. Journal Of Neurosurgery 2024, 142: 684-692. PMID: 39454218, DOI: 10.3171/2024.6.jns241111.Peer-Reviewed Original ResearchCitationsAltmetricIntravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series
Hirota R, Sasaki M, Iyama S, Kurihara K, Fukushi R, Obara H, Oshigiri T, Morita T, Nakazaki M, Namioka T, Namioka A, Onodera R, Kataoka-Sasaki Y, Oka S, Takemura M, Ukai R, Yokoyama T, Sasaki Y, Yamashita T, Kobayashi M, Okuma Y, Kondo R, Aichi R, Ohmatsu S, Kawashima N, Ito Y, Kobune M, Takada K, Ishiai S, Ogata T, Teramoto A, Yamashita T, Kocsis J, Honmou O. Intravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series. Journal Of Clinical Medicine 2024, 13: 6072. PMID: 39458022, PMCID: PMC11509003, DOI: 10.3390/jcm13206072.Peer-Reviewed Original ResearchCitations
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