Publications

2022

A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized ¹H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator.Miller CO, Gantert LT, Previs SF, Chen Y, Anderson KD, Thomas JM, Sanacora G, Uslaner JM, Rothman DL, Mason GF. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Jun; 2020 Sep 29. PMID: 33309567.
Evaluation of the Trajectory of Depression Severity With Ketamine and Esketamine Treatment in a Clinical Setting.Nikayin S, Rhee TG, Cunningham ME, de Fontnouvelle CA, Ostroff RB, Sanacora G, Wilkinson ST. JAMA Psychiatry. 2022 May 11; 2022 May 11. PMID: 35544190.
Comparison of Long-Term Efficacy and Safety of Esketamine Nasal Spray Plus Oral Antidepressant in Younger Versus Older Patients With Treatment-Resistant Depression: Post-Hoc Analysis of SUSTAIN-2, a Long-Term Open-Label Phase 3 Safety and Efficacy Study.Ochs-Ross R, Wajs E, Daly EJ, Zhang Y, Lane R, Lim P, Drevets WC, Steffens DC, Sanacora G, Jamieson C, Hough D, Manji H, Singh JB. Am J Geriatr Psychiatry. 2022 May; 2021 Oct 6. PMID: 34750057.
mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression.Averill LA, Averill CL, Gueorguieva R, Fouda S, Sherif M, Ahn KH, Ranganathan M, D'Souza DC, Southwick SM, Sanacora G, Duman RS, Krystal JH, Abdallah CG. J Affect Disord. 2022 Apr 15; 2022 Jan 29. PMID: 35101523.
Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans.Averill LA, Jiang L, Purohit P, Coppoli A, Averill CL, Roscoe J, Kelmendi B, De Feyter HM, de Graaf RA, Gueorguieva R, Sanacora G, Krystal JH, Rothman DL, Mason GF, Abdallah CG. Chronic Stress (Thousand Oaks). 2022 Jan-Dec; 2022 Apr 11. PMID: 35434443.
Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.Holmes SE, Finnema SJ, Naganawa M, DellaGioia N, Holden D, Fowles K, Davis M, Ropchan J, Emory P, Ye Y, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Mol Psychiatry. 2022 Apr; 2022 Feb 15. PMID: 35165397.
Ketamine in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review.Bandeira ID, Lins-Silva DH, Cavenaghi VB, Dorea-Bandeira I, Faria-Guimarães D, Barouh JL, Jesus-Nunes AP, Beanes G, Souza LS, Leal GC, Sanacora G, Miguel EC, Sampaio AS, Quarantini LC. Harv Rev Psychiatry. 2022 Mar-Apr 01. PMID: 35267254.
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders.Sanacora G, Yan Z, Popoli M. Nat Rev Neurosci. 2022 Feb; 2021 Dec 10. PMID: 34893785.

2021

Correction to: Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS).Pizzagalli DA, Smoski M, Ang YS, Whitton AE, Sanacora G, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu DV, Murrough JW, Yang H, Weiner RD, Calabrese JR, Goodman W, Potter WZ, Krystal AD. Neuropsychopharmacology. 2021 Nov. PMID: 34389811.
Evaluating the Role of Ketamine/Esketamine in the Management of Major Depressive Disorder with Suicide Risk.Nikayin S, Sanacora G. CNS Drugs. 2021 Oct; 2021 Sep 7. PMID: 34491545.
Cell-type specific modulation of NMDA receptors triggers antidepressant actions.Pothula S, Kato T, Liu RJ, Wu M, Gerhard D, Shinohara R, Sliby AN, Chowdhury GMI, Behar KL, Sanacora G, Banerjee P, Duman RS. Mol Psychiatry. 2021 Sep; 2020 Jun 2. PMID: 32488125.
The effect of single administration of intravenous ketamine augmentation on suicidal ideation in treatment-resistant unipolar depression: Results from a randomized double-blind study.Feeney A, Hock RS, Freeman MP, Flynn M, Hoeppner B, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Fava M, Papakostas GI. Eur Neuropsychopharmacol. 2021 Aug; 2021 Jun 3. PMID: 34090255.
Macro- and Microscale Stress-Associated Alterations in Brain Structure: Translational Link With Depression.Banasr M, Sanacora G, Esterlis I. Biol Psychiatry. 2021 Jul 15; 2021 Apr 16. PMID: 34001371.
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.Levey DF, Stein MB, Wendt FR, Pathak GA, Zhou H, Aslan M, Quaden R, Harrington KM, Nuñez YZ, Overstreet C, Radhakrishnan K, Sanacora G, McIntosh AM, Shi J, Shringarpure SS, Concato J, Polimanti R, Gelernter J. Nat Neurosci. 2021 Jul; 2021 May 27. PMID: 34045744.
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.McIntyre RS, Rosenblat JD, Nemeroff CB, Sanacora G, Murrough JW, Berk M, Brietzke E, Dodd S, Gorwood P, Ho R, Iosifescu DV, Lopez Jaramillo C, Kasper S, Kratiuk K, Lee JG, Lee Y, Lui LMW, Mansur RB, Papakostas GI, Subramaniapillai M, Thase M, Vieta E, Young AH, Zarate CA Jr, Stahl S. Am J Psychiatry. 2021 May 1; 2021 Mar 17. PMID: 33726522.
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality.Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Epilepsia. 2021 May; 2021 Mar 10. PMID: 33751566.
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.Dwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Am J Psychiatry. 2021 Apr 1; 2021 Mar 3. PMID: 33653121.
Intravenous arketamine for treatment-resistant depression: open-label pilot study.Leal GC, Bandeira ID, Correia-Melo FS, Telles M, Mello RP, Vieira F, Lima CS, Jesus-Nunes AP, Guerreiro-Costa LNF, Marback RF, Caliman-Fontes AT, Marques BLS, Bezerra MLO, Dias-Neto AL, Silva SS, Sampaio AS, Sanacora G, Turecki G, Loo C, Lacerda ALT, Quarantini LC. Eur Arch Psychiatry Clin Neurosci. 2021 Apr; 2020 Feb 20. PMID: 32078034.
Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial.Wilkinson ST, Rhee TG, Joormann J, Webler R, Ortiz Lopez M, Kitay B, Fasula M, Elder C, Fenton L, Sanacora G. Psychother Psychosom. 2021; 2021 Jun 29. PMID: 34186531.

2020

Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS).Pizzagalli DA, Smoski M, Ang YS, Whitton AE, Sanacora G, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu DV, Murrough JW, Yang H, Weiner RD, Calabrese JR, Goodman W, Potter WZ, Krystal AD. Neuropsychopharmacology. 2020 Sep; 2020 Jun 16. PMID: 32544925.
Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul. PMID: 30617276.
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul; 2018 Oct 3. PMID: 30283029.
Early life stress and glutamate neurotransmission in major depressive disorder.Averill LA, Abdallah CG, Fenton LR, Fasula MK, Jiang L, Rothman DL, Mason GF, Sanacora G. Eur Neuropsychopharmacol. 2020 Jun; 2020 May 15. PMID: 32418842.
Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression?Sanacora G. JAMA Psychiatry. 2020 Jun 1. PMID: 32074267.
Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Patients Who Have Active Suicidal Ideation With Intent: Double-Blind, Randomized Study (ASPIRE I).Fu DJ, Ionescu DF, Li X, Lane R, Lim P, Sanacora G, Hough D, Manji H, Drevets WC, Canuso CM. J Clin Psychiatry. 2020 May 12; 2020 May 12. PMID: 32412700.
Body Mass Index as a Moderator of Treatment Response to Ketamine for Major Depressive Disorder.Freeman MP, Hock RS, Papakostas GI, Judge H, Cusin C, Mathew SJ, Sanacora G, Iosifescu DV, DeBattista C, Trivedi MH, Fava M. J Clin Psychopharmacol. 2020 May/Jun. PMID: 32332464.
A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K, Potter WZ. Nat Med. 2020 May; 2020 Mar 30. PMID: 32231295.
Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin.Abdallah CG, Averill LA, Gueorguieva R, Goktas S, Purohit P, Ranganathan M, Sherif M, Ahn KH, D'Souza DC, Formica R, Southwick SM, Duman RS, Sanacora G, Krystal JH. Neuropsychopharmacology. 2020 May; 2020 Feb 24. PMID: 32092760.
Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression: Assessment of Long-Term Safety in a Phase 3, Open-Label Study (SUSTAIN-2).Wajs E, Aluisio L, Holder R, Daly EJ, Lane R, Lim P, George JE, Morrison RL, Sanacora G, Young AH, Kasper S, Sulaiman AH, Li CT, Paik JW, Manji H, Hough D, Grunfeld J, Jeon HJ, Wilkinson ST, Drevets WC, Singh JB. J Clin Psychiatry. 2020 Apr 28; 2020 Apr 28. PMID: 32316080.
Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression-TRANSFORM-3.Ochs-Ross R, Daly EJ, Zhang Y, Lane R, Lim P, Morrison RL, Hough D, Manji H, Drevets WC, Sanacora G, Steffens DC, Adler C, McShane R, Gaillard R, Wilkinson ST, Singh JB. Am J Geriatr Psychiatry. 2020 Feb; 2019 Oct 17. PMID: 31734084.
Time to relapse after a single administration of intravenous ketamine augmentation in unipolar treatment-resistant depression.Salloum NC, Fava M, Hock RS, Freeman MP, Flynn M, Hoeppner B, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI. J Affect Disord. 2020 Jan 1; 2019 Sep 3. PMID: 31494365.

2019

Lower synaptic density is associated with depression severity and network alterations.Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Nat Commun. 2019 Apr 4; 2019 Apr 4. PMID: 30948709.
Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.Duman RS, Sanacora G, Krystal JH. Neuron. 2019 Apr 3. PMID: 30946828.
Ketamine: A Paradigm Shift for Depression Research and Treatment.Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Neuron. 2019 Mar 6. PMID: 30844397.
Caution Against Overinterpreting Opiate Receptor Stimulation as Mediating Antidepressant Effects of Ketamine.Sanacora G. Am J Psychiatry. 2019 Mar 1. PMID: 30818992.
Efficacy of intravenous ketamine treatment in anxious versus nonanxious unipolar treatment-resistant depression.Salloum NC, Fava M, Freeman MP, Flynn M, Hoeppner B, Hock RS, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI. Depress Anxiety. 2019 Mar; 2018 Dec 30. PMID: 30597688.
Sex differences in response to ketamine as a rapidly acting intervention for treatment resistant depression.Freeman MP, Papakostas GI, Hoeppner B, Mazzone E, Judge H, Cusin C, Mathew S, Sanacora G, Iosifescu D, DeBattista C, Trivedi MH, Fava M. J Psychiatr Res. 2019 Mar; 2019 Jan 8. PMID: 30641350.
ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol.Mathew SJ, Wilkinson ST, Altinay M, Asghar-Ali A, Chang LC, Collins KA, Dale RM, Hu B, Krishnan K, Kellner CH, Malone DA, Murrough JW, Ostroff RB, Sanacora G, Shao M, Anand A. Contemp Clin Trials. 2019 Feb; 2018 Dec 17. PMID: 30572160.
A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems.Wilkinson ST, Sanacora G. Drug Discov Today. 2019 Feb; 2018 Nov 14. PMID: 30447328.
Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study.Canuso CM, Singh JB, Fedgchin M, Alphs L, Lane R, Lim P, Pinter C, Hough D, Sanacora G, Manji H, Drevets WC. Focus (Am Psychiatr Publ). 2019 Jan; 2019 Jan 7. PMID: 32015715.

2018

The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development.Krystal AD, Pizzagalli DA, Mathew SJ, Sanacora G, Keefe R, Song A, Calabrese J, Goddard A, Goodman W, Lisanby SH, Smoski M, Weiner R, Iosifescu D, Nurnberger J Jr, Szabo S, Murrough J, Shekhar A, Potter W. Nat Rev Drug Discov. 2018 Dec 28. PMID: 30591715.
The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?Abdallah CG, Sanacora G, Duman RS, Krystal JH. Pharmacol Ther. 2018 Oct; 2018 May 25. PMID: 29803629.
The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF. Neuropsychopharmacology. 2018 Sep; 2018 Jun 28. PMID: 29977074.
Acute and Longer-Term Outcomes Using Ketamine as a Clinical Treatment at the Yale Psychiatric Hospital.Wilkinson ST, Katz RB, Toprak M, Webler R, Ostroff RB, Sanacora G. J Clin Psychiatry. 2018 Jul 24; 2018 Jul 24. PMID: 30063304.
Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study.Canuso CM, Singh JB, Fedgchin M, Alphs L, Lane R, Lim P, Pinter C, Hough D, Sanacora G, Manji H, Drevets WC. Am J Psychiatry. 2018 Jul 1; 2018 Apr 16. PMID: 29656663.
Hopes and Skepticism for Unraveling the Unique Mechanisms of Ketamine's Rapid Onset Antidepressant Actions in Rodent Models.Sanacora G. Biol Psychiatry. 2018 Jul 1. PMID: 29929579.
Ketamine: A Review for Clinicians.Sanacora G, Katz R. Focus (Am Psychiatr Publ). 2018 Jul; 2018 Jul 16. PMID: 31975918.
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [¹¹C]ABP688 and PET imaging study in depression.Esterlis I, DellaGioia N, Pietrzak RH, Matuskey D, Nabulsi N, Abdallah CG, Yang J, Pittenger C, Sanacora G, Krystal JH, Parsey RV, Carson RE, DeLorenzo C. Mol Psychiatry. 2018 Apr; 2017 Apr 11. PMID: 28397841.
Authorship Credit for Large Clinical Trials.Wilkinson ST, Sanacora G. JAMA. 2018 Feb 20. PMID: 29466586.
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA Jr, Sanacora G. Am J Psychiatry. 2018 Feb 1; 2017 Oct 3. PMID: 28969441.
Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale.van Schalkwyk GI, Wilkinson ST, Davidson L, Silverman WK, Sanacora G. J Affect Disord. 2018 Feb; 2017 Sep 28. PMID: 29045915.
Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Hoeppner BB, Shelton R, Iosifescu DV, Murrough JW, Mischoulon D, Cusin C, Rapaport M, Dunlop BW, Trivedi MH, Jha M, Sanacora G, Hermes G, Papakostas GI. Brain Stimul. 2018 Jan - Feb; 2017 Sep 23. PMID: 29030111.
Concurrent use of ketamine and monoamine oxidase inhibitors in the treatment of depression: A letter to the editor.Katz RB, Toprak M, Wilkinson ST, Sanacora G, Ostroff R. Gen Hosp Psychiatry. 2018 Sep - Oct; 2018 May 22. PMID: 30100209.

2017

A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Comparison Design Trial of Adjunctive Riluzole for Treatment-Resistant Major Depressive Disorder.Mathew SJ, Gueorguieva R, Brandt C, Fava M, Sanacora G. Neuropsychopharmacology. 2017 Dec; 2017 May 29. PMID: 28553836.
Considerations on the Off-label Use of Ketamine as a Treatment for Mood Disorders.Wilkinson ST, Sanacora G. JAMA. 2017 Sep 5. PMID: 28806440.
Reply to: Ketamine and Psychosis History: Antidepressant Efficacy and Psychotomimetic Effects Postinfusion.Medeiros da Frota Ribeiro C, Sanacora G, Ostroff R. Biol Psychiatry. 2017 Sep 1; 2017 Jan 23. PMID: 28262251.
Co-occurring Catatonia and Posterior Reversible Encephalopathy Syndrome Responsive to Electroconvulsive Therapy.Klingensmith KE, Sanacora G, Ostroff R. J ECT. 2017 Sep. PMID: 28383349.
Ketamine for the Treatment of Depression-Reply.Sanacora G. JAMA Psychiatry. 2017 Sep 1. PMID: 28700772.
Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Curr Psychiatry Rep. 2017 Aug 26; 2017 Aug 26. PMID: 28844076.
A Survey of the Clinical, Off-Label Use of Ketamine as a Treatment for Psychiatric Disorders.Wilkinson ST, Toprak M, Turner MS, Levine SP, Katz RB, Sanacora G. Am J Psychiatry. 2017 Jul 1. PMID: 28669202.
Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study.Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, Esterlis I. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jul; 2017 Apr 6. PMID: 28993818.
Hippocampal volume changes following electroconvulsive therapy: a systematic review and meta-analysis.Wilkinson ST, Sanacora G, Bloch MH. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 May; 2017 Feb 5. PMID: 28989984.
Balancing the Promise and Risks of Ketamine Treatment for Mood Disorders.Sanacora G, Heimer H, Hartman D, Mathew SJ, Frye M, Nemeroff C, Robinson Beale R. Neuropsychopharmacology. 2017 May; 2016 Sep 19. PMID: 27640324.
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders.Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, Summergrad P, Nemeroff CB. JAMA Psychiatry. 2017 Apr 1. PMID: 28249076.
Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy.Wilkinson ST, Ostroff RB, Sanacora G. J ECT. 2017 Mar. PMID: 27564424.
Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study.Sanacora G, Johnson MR, Khan A, Atkinson SD, Riesenberg RR, Schronen JP, Burke MA, Zajecka JM, Barra L, Su HL, Posener JA, Bui KH, Quirk MC, Piser TM, Mathew SJ, Pathak S. Neuropsychopharmacology. 2017 Mar; 2016 Sep 29. PMID: 27681442.
Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression.Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Chronic Stress (Thousand Oaks). 2017 Feb; 2017 Aug 3. PMID: 28835932.
Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects.Chowdhury GM, Zhang J, Thomas M, Banasr M, Ma X, Pittman B, Bristow L, Schaeffer E, Duman RS, Rothman DL, Behar KL, Sanacora G. Mol Psychiatry. 2017 Jan; 2016 Apr 12. PMID: 27067013.
Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.Haroon E, Miller AH, Sanacora G. Neuropsychopharmacology. 2017 Jan; 2016 Sep 15. PMID: 27629368.
Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression.Wilkinson ST, Wright D, Fasula MK, Fenton L, Griepp M, Ostroff RB, Sanacora G. Psychother Psychosom. 2017; 2017 May 11. PMID: 28490030.

2016

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression.Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, Van Nueten L. Am J Psychiatry. 2016 Aug 1; 2016 Apr 8. PMID: 27056608.
KETAMINE: A POTENTIAL RAPID-ACTING ANTISUICIDAL AGENT?Wilkinson ST, Sanacora G. Depress Anxiety. 2016 Aug; 2016 Apr 15. PMID: 27082101.
KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH. Depress Anxiety. 2016 Aug; 2016 Apr 6. PMID: 27062302.
Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AFT, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA Jr, Carter CS, Cook EH Jr, Daskalakis ZJ, DiLeone RJ, Duman RS, Grace AA, Hariri AR, Harrison PJ, Hiroi N, Kenny PJ, Kleinman JE, Krystal AD, Lewis DA, Lipska BK, Marder SR, Mason GF, Mathalon DH, McClung CA, McDougle CJ, McIntosh AM, McMahon FJ, Mirnics K, Monteggia LM, Narendran R, Nestler EJ, Neumeister A, O'Donovan MC, Öngür D, Pariante CM, Paulus MP, Pearlson G, Phillips ML, Pine DS, Pizzagalli DA, Pletnikov MV, Ragland JD, Rapoport JL, Ressler KJ, Russo SJ, Sanacora G, Sawa A, Schatzberg AF, Shaham Y, Shamay-Tsoory SG, Sklar P, State MW, Stein MB, Strakowski SM, Taylor SF, Turecki G, Turetsky BI, Weissman MM, Zachariou V, Zarate CA Jr, Zubieta JK. Biol Psychiatry. 2016 Jul 15. PMID: 27346079.
What Are We Learning From Early-Phase Clinical Trials With Glutamate Targeting Medications for the Treatment of Major Depressive Disorder.Sanacora G. JAMA Psychiatry. 2016 Jul 1. PMID: 27303925.
The Use of Ketamine for the Treatment of Depression in the Context of Psychotic Symptoms: To the Editor.da Frota Ribeiro CM, Sanacora G, Hoffman R, Ostroff R. Biol Psychiatry. 2016 May 1; 2015 Jun 4. PMID: 26212896.
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Nat Med. 2016 Mar. PMID: 26937618.

2015

A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder.Niciu MJ, Abdallah CG, Fenton LR, Fasula MK, Black A, Anderson GM, Sanacora G. J Affect Disord. 2015 Nov 15; 2015 Aug 19. PMID: 26363143.
Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a pilot randomized placebo-controlled trial.Pittenger C, Bloch MH, Wasylink S, Billingslea E, Simpson R, Jakubovski E, Kelmendi B, Sanacora G, Coric V. J Clin Psychiatry. 2015 Aug. PMID: 26214725.
Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders?Sanacora G, Schatzberg AF. Neuropsychopharmacology. 2015 Mar 13; 2015 Mar 13. PMID: 25767082.
In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I. Biol Psychiatry. 2015 Feb 1; 2014 Jul 10. PMID: 25156701.
Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.Abdallah CG, Sanacora G, Duman RS, Krystal JH. Annu Rev Med. 2015; 2014 Oct 17. PMID: 25341010.
Regulation of extrasynaptic glutamate levels as a pathophysiological mechanism in disorders of motivation and addiction.McCullumsmith RE, Sanacora G. Neuropsychopharmacology. 2015 Jan. PMID: 25482181.
Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders?Sanacora G, Schatzberg AF. Neuropsychopharmacology. 2015 Jan; 2014 Sep 26. PMID: 25257213.

2014

Glutamate metabolism in major depressive disorder.Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G. Am J Psychiatry. 2014 Dec 1; 2014 Oct 31. PMID: 25073688.
Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects.Sanacora G, Smith MA, Pathak S, Su HL, Boeijinga PH, McCarthy DJ, Quirk MC. Mol Psychiatry. 2014 Sep; 2013 Oct 15. PMID: 24126931.
Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder.Abdallah CG, Niciu MJ, Fenton LR, Fasula MK, Jiang L, Black A, Rothman DL, Mason GF, Sanacora G. Psychother Psychosom. 2014; 2014 Aug 6. PMID: 25116726.
Glial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity?Niciu MJ, Henter ID, Sanacora G, Zarate CA Jr. World J Biol Psychiatry. 2014 Jan; 2013 Sep 12. PMID: 24024876.

2013

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS. Biol Psychiatry. 2013 Nov 15; 2013 Jun 14. PMID: 23751205.
Delayed amnesic syndrome after riluzole use in major depressive disorder: a case report.Cardoos A, Inamori A, Sanacora G, Fava M, Mischoulon D. Psychosomatics. 2013 Sep-Oct; 2013 Mar 6. PMID: 23473447.
From pathophysiology to novel antidepressant drugs: glial contributions to the pathology and treatment of mood disorders.Sanacora G, Banasr M. Biol Psychiatry. 2013 Jun 15. PMID: 23726152.
Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond.Krystal JH, Sanacora G, Duman RS. Biol Psychiatry. 2013 Jun 15. PMID: 23726151.

2012

Effects of ketamine in treatment-refractory obsessive-compulsive disorder.Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Biol Psychiatry. 2012 Dec 1; 2012 Jul 10. PMID: 22784486.
Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C Jr. Biol Psychiatry. 2012 Dec 1; 2012 Jul 6. PMID: 22771240.
Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting.Abdallah CG, Fasula M, Kelmendi B, Sanacora G, Ostroff R. J ECT. 2012 Sep. PMID: 22847373.
¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism.Chowdhury GM, Behar KL, Cho W, Thomas MA, Rothman DL, Sanacora G. Biol Psychiatry. 2012 Jun 1; 2011 Dec 9. PMID: 22169441.
Cortical GABA levels in primary insomnia.Morgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G. Sleep. 2012 Jun 1; 2012 Jun 1. PMID: 22654200.
Glutamate-based depression GBD.McCarthy DJ, Alexander R, Smith MA, Pathak S, Kanes S, Lee CM, Sanacora G. Med Hypotheses. 2012 May; 2012 Mar 4. PMID: 22391030.
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla.Gomez R, Behar KL, Watzl J, Weinzimer SA, Gulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF. Biol Psychiatry. 2012 Feb 1; 2011 Aug 19. PMID: 21855054.
The roles of glutamate receptors across major neurological and psychiatric disorders.Siegel S, Sanacora G. Pharmacol Biochem Behav. 2012 Feb; 2011 Nov 13. PMID: 22108650.

Publications

2022

Evaluation of the Trajectory of Depression Severity With Ketamine and Esketamine Treatment in a Clinical Setting.Nikayin S, Rhee TG, Cunningham ME, de Fontnouvelle CA, Ostroff RB, Sanacora G, Wilkinson ST. JAMA Psychiatry. 2022 May 11; 2022 May 11. PMID: 35544190.
An Update on Community Ketamine Practices.O'Brien B, Wilkinson ST, Mathew SJ. Am J Psychiatry. 2022 May. PMID: 35491568.
A Choice-Based Conjoint Analysis of the Psychiatrist Decision-Making Process Used in Determining When to Discharge Adults With Major Depressive Disorder Hospitalized for Active Suicidal Ideation With Intent.Voelker J, Wilkinson ST, Katz EG, Nash AI, Daly E, Ali A, Lovink A, Stahl J, Desai A, Kuvadia H, Neslusan C, Sheehan JJ. J Nerv Ment Dis. 2022 May 1. PMID: 34937847.
Long-term safety of ketamine and esketamine in treatment of depression.Nikayin S, Murphy E, Krystal JH, Wilkinson ST. Expert Opin Drug Saf. 2022 Apr 19; 2022 Apr 19. PMID: 35416105.
Pharmacological and somatic treatment effects on suicide in adults: A systematic review and meta-analysis.Wilkinson ST, Trujillo Diaz D, Rupp ZW, Kidambi A, Ramirez KL, Flores JM, Avila-Quintero VJ, Rhee TG, Olfson M, Bloch MH. Depress Anxiety. 2022 Feb; 2021 Nov 11. PMID: 34762330.

2021

Twenty-year trends in use of electroconvulsive therapy among homeless and domiciled veterans with mental illness.Tsai J, Szymkowiak D, Wilkinson ST, Holtzheimer PE. CNS Spectr. 2021 Dec 13; 2021 Dec 13. PMID: 34895380.
Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients.Rhee TG, Sint K, Olfson M, Gerhard T, H Busch S, Wilkinson ST. Am J Psychiatry. 2021 Dec; 2021 Sep 10. PMID: 34503341.
The Impact of Depression on Outcomes in Patients With Heart Failure and Reduced Ejection Fraction Treated in the GUIDE-IT Trial.Chouairi F, Fuery MA, Mullan CW, Caraballo C, Sen S, Maulion C, Wilkinson ST, Surti T, McCullough M, Miller PE, Pacor J, Leifer ES, Felker GM, Velazquez EJ, Fiuzat M, O'Connor CM, Januzzi JL, Desai NR, Ahmad T. J Card Fail. 2021 Dec; 2021 Jun 22. PMID: 34166799.
Utilization of Electroconvulsive Therapy for Older Homeless Adults Covered by Medicare.Wilkinson ST, Rhee TG, Tsai J. Psychiatr Q. 2021 Dec; 2021 Sep 1. PMID: 34468909.
Mental Health Care Resource Utilization and Barriers to Receiving Mental Health Services Among US Adults With a Major Depressive Episode and Suicidal Ideation or Behavior With Intent.Voelker J, Cai Q, Daly E, Connolly N, Pesa J, Sheehan JJ, Wilkinson ST. J Clin Psychiatry. 2021 Sep 14; 2021 Sep 14. PMID: 34529898.
Treatment Response With Esketamine Nasal Spray Plus an Oral Antidepressant in Patients With Treatment-Resistant Depression Without Evidence of Early Response: A Pooled Post Hoc Analysis of the TRANSFORM Studies.Turkoz I, Daly E, Singh J, Lin X, Tymofyeyev Y, Williamson D, Salvadore G, Nash AI, Macaluso M, Wilkinson ST, Nelson JC. J Clin Psychiatry. 2021 Jul 20; 2021 Jul 20. PMID: 34288609.
A Potential Case of Acute Ketamine Withdrawal: Clinical Implications for the Treatment of Refractory Depression.Roxas N, Ahuja C, Isom J, Wilkinson ST, Capurso N. Am J Psychiatry. 2021 Jul. PMID: 34270337.
Barriers to the Implementation of Electroconvulsive Therapy (ECT): Results From a Nationwide Survey of ECT Practitioners.Wilkinson ST, Kitay BM, Harper A, Rhee TG, Sint K, Ghosh A, Lopez MO, Saenz S, Tsai J. Psychiatr Serv. 2021 Jul 1; 2021 May 11. PMID: 33971727.
Emerging Therapeutics Based on the Amino Acid Neurotransmitter System: An Update on the Pharmaceutical Pipeline for Mood Disorders.Hecking J, Davoudian PA, Wilkinson ST. Chronic Stress (Thousand Oaks). 2021 Jan-Dec; 2021 Jun 2. PMID: 34124495.
Repetitive and Self-injurious Behaviors in Children with Cornelia de Lange Syndrome.Srivastava S, Clark B, Landy-Schmitt C, Offermann EA, Kline AD, Wilkinson ST, Grados MA. J Autism Dev Disord. 2021 May. PMID: 32809170.
Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial.Wilkinson ST, Rhee TG, Joormann J, Webler R, Ortiz Lopez M, Kitay B, Fasula M, Elder C, Fenton L, Sanacora G. Psychother Psychosom. 2021; 2021 Jun 29. PMID: 34186531.

2020

Prevalence of Treatment for Depression Among US Adults Who Screen Positive for Depression, 2007-2016.Rhee TG, Wilkinson ST, Steffens DC, Rosenheck RA, Olfson M. JAMA Psychiatry. 2020 Nov 1. PMID: 32609306.
20-Year Trends in the Pharmacologic Treatment of Bipolar Disorder by Psychiatrists in Outpatient Care Settings.Rhee TG, Olfson M, Nierenberg AA, Wilkinson ST. Am J Psychiatry. 2020 Aug 1; 2020 Apr 21. PMID: 32312111.
Characterization of the Quality of Electroconvulsive Therapy Among Older Medicare Beneficiaries.Rhee TG, Olfson M, Sint K, Wilkinson ST. J Clin Psychiatry. 2020 Jul 7; 2020 Jul 7. PMID: 32659875.
Exploring the Psychiatrist-Industry Financial Relationship: Insight from the Open Payment Data of Centers for Medicare and Medicaid Services.Rhee TG, Wilkinson ST. Adm Policy Ment Health. 2020 Jul. PMID: 31916072.
Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul. PMID: 30617276.
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI. Mol Psychiatry. 2020 Jul; 2018 Oct 3. PMID: 30283029.
Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression: Assessment of Long-Term Safety in a Phase 3, Open-Label Study (SUSTAIN-2).Wajs E, Aluisio L, Holder R, Daly EJ, Lane R, Lim P, George JE, Morrison RL, Sanacora G, Young AH, Kasper S, Sulaiman AH, Li CT, Paik JW, Manji H, Hough D, Grunfeld J, Jeon HJ, Wilkinson ST, Drevets WC, Singh JB. J Clin Psychiatry. 2020 Apr 28; 2020 Apr 28. PMID: 32316080.
Suicide in Older Adults With and Without Known Mental Illness: Results From the National Violent Death Reporting System, 2003-2016.Schmutte TJ, Wilkinson ST. Am J Prev Med. 2020 Apr; 2020 Jan 28. PMID: 32001049.
A Measure to Assess Perceptions and Knowledge About Electroconvulsive Therapy: Development and Psychometric Properties.Tsai J, Huang M, Wilkinson ST, Edelen C, Rosenheck RA, Holtzheimer PE. J ECT. 2020 Mar. PMID: 31192871.
Effects of video psychoeducation on perceptions and knowledge about electroconvulsive therapy.Tsai J, Huang M, Wilkinson ST, Edelen C. Psychiatry Res. 2020 Feb 3; 2020 Feb 3. PMID: 32192999.
Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression-TRANSFORM-3.Ochs-Ross R, Daly EJ, Zhang Y, Lane R, Lim P, Morrison RL, Hough D, Manji H, Drevets WC, Sanacora G, Steffens DC, Adler C, McShane R, Gaillard R, Wilkinson ST, Singh JB. Am J Geriatr Psychiatry. 2020 Feb; 2019 Oct 17. PMID: 31734084.
Clinical overview of NMDA-R antagonists and clinical practice.Davoudian PA, Wilkinson ST. Adv Pharmacol. 2020; 2020 Jun 1. PMID: 32616204.
Changes in pharmacotherapeutic approaches in the treatment of bipolar disorder by primary care physicians.Rhee TG, Olfson M, Wilkinson ST. Gen Hosp Psychiatry. 2020 Nov - Dec; 2020 Mar 14. PMID: 32184005.

2019

Longer-term open-label study of adjunctive riluzole in treatment-resistant depression.Sakurai H, Dording C, Yeung A, Foster S, Jain F, Chang T, Trinh NH, Bernard R, Boyden S, Iqbal SZ, Wilkinson ST, Mathew SJ, Mischoulon D, Fava M, Cusin C. J Affect Disord. 2019 Nov 1; 2019 Jul 2. PMID: 31400624.
Associations of Adverse Childhood Experiences with Past-Year DSM-5 Psychiatric and Substance Use Disorders in Older Adults.Rhee TG, Barry LC, Kuchel GA, Steffens DC, Wilkinson ST. J Am Geriatr Soc. 2019 Oct; 2019 Jun 17. PMID: 31206597.
Psychiatric Practice Patterns and Barriers to the Adoption of Esketamine.Wilkinson ST, Howard DH, Busch SH. JAMA. 2019 Sep 17. PMID: 31373610.
Impact of midazolam vs. saline on effect size estimates in controlled trials of ketamine as a rapid-acting antidepressant.Wilkinson ST, Farmer C, Ballard ED, Mathew SJ, Grunebaum MF, Murrough JW, Sos P, Wang G, Gueorguieva R, Zarate CA Jr. Neuropsychopharmacology. 2019 Jun; 2019 Jan 17. PMID: 30653192.
Leveraging Neuroplasticity to Enhance Adaptive Learning: The Potential for Synergistic Somatic-Behavioral Treatment Combinations to Improve Clinical Outcomes in Depression.Wilkinson ST, Holtzheimer PE, Gao S, Kirwin DS, Price RB. Biol Psychiatry. 2019 Mar 15; 2018 Sep 20. PMID: 30528745.
The Successful Use of Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and a Pituitary Lesion.Kitay BM, Katz RB, Wilkinson ST, Ostroff RB. J ECT. 2019 Mar. PMID: 29952859.
Access to Outpatient Electroconvulsive Therapy at VA Medical Centers - Reply.Wilkinson ST, Rosenheck R. J ECT. 2019 Mar. PMID: 29901498.
ELEctroconvulsive therapy (ECT) vs. Ketamine in patients with Treatment-resistant Depression: The ELEKT-D study protocol.Mathew SJ, Wilkinson ST, Altinay M, Asghar-Ali A, Chang LC, Collins KA, Dale RM, Hu B, Krishnan K, Kellner CH, Malone DA, Murrough JW, Ostroff RB, Sanacora G, Shao M, Anand A. Contemp Clin Trials. 2019 Feb; 2018 Dec 17. PMID: 30572160.
A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems.Wilkinson ST, Sanacora G. Drug Discov Today. 2019 Feb; 2018 Nov 14. PMID: 30447328.

2018

Serum and plasma brain-derived neurotrophic factor and response in a randomized controlled trial of riluzole for treatment resistant depression.Wilkinson ST, Kiselycznyk C, Banasr M, Webler RD, Haile C, Mathew SJ. J Affect Disord. 2018 Dec 1; 2018 Aug 18. PMID: 30153634.
Acute and Longer-Term Outcomes Using Ketamine as a Clinical Treatment at the Yale Psychiatric Hospital.Wilkinson ST, Katz RB, Toprak M, Webler R, Ostroff RB, Sanacora G. J Clin Psychiatry. 2018 Jul 24; 2018 Jul 24. PMID: 30063304.
Identifying Recipients of Electroconvulsive Therapy: Data From Privately Insured Americans.Wilkinson ST, Agbese E, Leslie DL, Rosenheck RA. Psychiatr Serv. 2018 May 1; 2018 Feb 1. PMID: 29385954.
Authorship Credit for Large Clinical Trials.Wilkinson ST, Sanacora G. JAMA. 2018 Feb 20. PMID: 29466586.
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA Jr, Sanacora G. Am J Psychiatry. 2018 Feb 1; 2017 Oct 3. PMID: 28969441.
Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale.van Schalkwyk GI, Wilkinson ST, Davidson L, Silverman WK, Sanacora G. J Affect Disord. 2018 Feb; 2017 Sep 28. PMID: 29045915.
Concurrent use of ketamine and monoamine oxidase inhibitors in the treatment of depression: A letter to the editor.Katz RB, Toprak M, Wilkinson ST, Sanacora G, Ostroff R. Gen Hosp Psychiatry. 2018 Sep - Oct; 2018 May 22. PMID: 30100209.

2017

Electroconvulsive Therapy at a Veterans Health Administration Medical Center.Wilkinson ST, Rosenheck RA. J ECT. 2017 Dec. PMID: 28272097.
Considerations on the Off-label Use of Ketamine as a Treatment for Mood Disorders.Wilkinson ST, Sanacora G. JAMA. 2017 Sep 5. PMID: 28806440.
A Survey of the Clinical, Off-Label Use of Ketamine as a Treatment for Psychiatric Disorders.Wilkinson ST, Toprak M, Turner MS, Levine SP, Katz RB, Sanacora G. Am J Psychiatry. 2017 Jul 1. PMID: 28669202.
Hippocampal volume changes following electroconvulsive therapy: a systematic review and meta-analysis.Wilkinson ST, Sanacora G, Bloch MH. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 May; 2017 Feb 5. PMID: 28989984.
Ketamine as a Treatment for Adolescent Depression: A Case Report.Dwyer JB, Beyer C, Wilkinson ST, Ostroff RB, Qayyum Z, Bloch MH. J Am Acad Child Adolesc Psychiatry. 2017 Apr. PMID: 28335880.
Successful Treatment With Electroconvulsive Therapy of a Patient With Bipolar Disorder and a 7-mm Cerebral Aneurysm.Toprak M, Wilkinson ST, Ostroff RB. J ECT. 2017 Mar. PMID: 28072662.
Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy.Wilkinson ST, Ostroff RB, Sanacora G. J ECT. 2017 Mar. PMID: 27564424.
Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression.Wilkinson ST, Wright D, Fasula MK, Fenton L, Griepp M, Ostroff RB, Sanacora G. Psychother Psychosom. 2017; 2017 May 11. PMID: 28490030.

2016

Analyzing Patterns of Community Interest at a Legacy Mining Waste Site to Assess and Inform Environmental Health Literacy Efforts.Ramirez-Andreotta MD, Lothrop N, Wilkinson ST, Root RA, Artiola JF, Klimecki W, Loh M. J Environ Stud Sci. 2016 Sep; 2015 Jul 21. PMID: 27595054.
KETAMINE: A POTENTIAL RAPID-ACTING ANTISUICIDAL AGENT?Wilkinson ST, Sanacora G. Depress Anxiety. 2016 Aug; 2016 Apr 15. PMID: 27082101.
A Systematic Review of the Evidence for Medical Marijuana in Psychiatric Indications.Wilkinson ST, Radhakrishnan R, D'Souza DC. J Clin Psychiatry. 2016 Aug. PMID: 27561138.
Multimedia exposures to arsenic and lead for children near an inactive mine tailings and smelter site.Loh MM, Sugeng A, Lothrop N, Klimecki W, Cox M, Wilkinson ST, Lu Z, Beamer PI. Environ Res. 2016 Apr; 2016 Jan 21. PMID: 26803211.
The Formation of Marijuana Risk Perception in a Population of Substance Abusing Patients.Wilkinson ST, van Schalkwyk GI, Davidson L, D'Souza DC. Psychiatr Q. 2016 Mar. PMID: 25982082.
Marijuana Legalization: Impact on Physicians and Public Health.Wilkinson ST, Yarnell S, Radhakrishnan R, Ball SA, D'Souza DC. Annu Rev Med. 2016; 2015 Oct 19. PMID: 26515984.

2015

Marijuana use is associated with worse outcomes in symptom severity and violent behavior in patients with posttraumatic stress disorder.Wilkinson ST, Stefanovics E, Rosenheck RA. J Clin Psychiatry. 2015 Sep. PMID: 26455669.
Hickam's dictum and the rare convergence of antisynthetase syndrome and hemoglobin SC disease.Wilkinson ST, Grunwald MR, Paik JJ, Ostrow LW, Gelber AC. QJM. 2015 Sep; 2014 Dec 16. PMID: 25519232.
Home Water Treatment Habits and Effectiveness in a Rural Arizona Community.Lothrop N, Wilkinson ST, Verhougstraete M, Sugeng A, Loh MM, Klimecki W, Beamer PI. Water (Basel). 2015. PMID: 26120482.

2014

Electroconvulsive therapy and cerebral aneurysms.Wilkinson ST, Helgeson L, Ostroff RB. J ECT. 2014 Dec. PMID: 25010028.
Medicalization of marijuana--reply.Wilkinson ST, D'Souza DC. JAMA. 2014 Nov 12. PMID: 25387198.
Effects of a hospitalwide pharmacy practice model change on readmission and return to emergency department rates.Anderegg SV, Wilkinson ST, Couldry RJ, Grauer DW, Howser E. Am J Health Syst Pharm. 2014 Sep 1. PMID: 25147171.
Delirium presenting as mania in a patient with end-stage COPD.Wilkinson ST, Chang SB, Foley T, Lipsey JR, MacKinnon DF. Am J Psychiatry. 2014 Aug. PMID: 25082489.
Mitochondria and redox homoeostasis as chemotherapeutic targets.Briehl MM, Tome ME, Wilkinson ST, Jaramillo MC, Lee K. Biochem Soc Trans. 2014 Aug. PMID: 25109983.
Problems with the medicalization of marijuana.Wilkinson ST, D'Souza DC. JAMA. 2014 Jun 18. PMID: 24845238.
Impact of Cannabis Use on the Development of Psychotic Disorders.Wilkinson ST, Radhakrishnan R, D'Souza DC. Curr Addict Rep. 2014 Jun 1. PMID: 25767748.
Preceptor development: providing effective feedback, part 2.Buck B, Wilkinson ST, Phillips H. Hosp Pharm. 2014 Jun. PMID: 24958969.
Gone to Pot - A Review of the Association between Cannabis and Psychosis.Radhakrishnan R, Wilkinson ST, D'Souza DC. Front Psychiatry. 2014; 2014 May 22. PMID: 24904437.
Use of dust fall filters as passive samplers for metal concentrations in air for communities near contaminated mine tailings.Beamer PI, Sugeng AJ, Kelly MD, Lothrop N, Klimecki W, Wilkinson ST, Loh M. Environ Sci Process Impacts. 2014 May. PMID: 24469149.
Reflections on residency: pre-rounding.Wilkinson ST. Yale J Biol Med. 2014 Mar; 2014 Mar 5. PMID: 24600340.

2013

Medical and recreational marijuana: commentary and review of the literature.Wilkinson ST. Mo Med. 2013 Nov-Dec. PMID: 24564006.
Methods to Promote Preceptor Scholarship through Resident Collaboration.Brown JN, Kemp DW, Parker MH, Wilkinson ST. Hosp Pharm. 2013 Sep. PMID: 24421534.
Optimizing the customized residency plan.Phillips H, Wilkinson ST, Buck B. Hosp Pharm. 2013 Jun. PMID: 24421508.
Can the targeted use of a discharge pharmacist significantly decrease 30-day readmissions?Pal A, Babbott S, Wilkinson ST. Hosp Pharm. 2013 May. PMID: 24421494.
Preceptor development: providing effective feedback.Wilkinson ST, Couldry R, Phillips H, Buck B. Hosp Pharm. 2013 Jan. PMID: 24421419.

2012

Leveraging drug-utilization and external benchmarking data to drive change in prescribing behaviors.O'Neal BC, Couldry RJ, Wilkinson ST, Cannella CA, Williams CB, Scott LA, Simpson SQ. Am J Health Syst Pharm. 2012 Nov 1. PMID: 23111677.
Lack and/or aberrant localization of major histocompatibility class II (MHCII) protein in plasmablastic lymphoma.Schmelz M, Montes-Moreno S, Piris M, Wilkinson ST, Rimsza LM. Haematologica. 2012 Oct; 2012 Jun 11. PMID: 22689685.
Partial plasma cell differentiation as a mechanism of lost major histocompatibility complex class II expression in diffuse large B-cell lymphoma.Wilkinson ST, Vanpatten KA, Fernandez DR, Brunhoeber P, Garsha KE, Glinsmann-Gibson BJ, Grogan TM, Teruya-Feldstein J, Rimsza LM. Blood. 2012 Feb 9; 2011 Dec 13. PMID: 22167754.
Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells.Wilkinson ST, Tome ME, Briehl MM. Int J Mol Sci. 2012; 2012 Aug 16. PMID: 22949856.

2010

Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma.Stasik CJ, Nitta H, Zhang W, Mosher CH, Cook JR, Tubbs RR, Unger JM, Brooks TA, Persky DO, Wilkinson ST, Grogan TM, Rimsza LM. Haematologica. 2010 Apr. PMID: 20378577.
Increased cytochrome c correlates with poor survival in aggressive lymphoma.Wilkinson ST, Johnson DB, Tardif HL, Tome ME, Briehl MM. Oncol Lett. 2010 Mar. PMID: 20798784.

2009

Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV.Wilkinson ST, Fernandez DR, Murphy SP, Braziel RM, Campo E, Chan WC, Delabie J, Gascoyne RD, Staudt LM, Jaffe ES, Rosenwald A, Rimsza LM. Leuk Lymphoma. 2009 Nov. PMID: 19814686.
Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells.James BP, Staatz WD, Wilkinson ST, Meuillet E, Powis G. Free Radic Biol Med. 2009 Mar 15; 2008 Dec 24. PMID: 19135146.

2007

Mutational analysis of H3 and H4 N termini reveals distinct roles in nuclear import.Blackwell JS Jr, Wilkinson ST, Mosammaparast N, Pemberton LF. J Biol Chem. 2007 Jul 13; 2007 May 15. PMID: 17507373.

2006

Acute renal failure associated with inhaled tobramycin.Cannella CA, Wilkinson ST. Am J Health Syst Pharm. 2006 Oct 1. PMID: 16990632.

1995

Resonant-cavity-enhanced thin-film AlGaAs/GaAs/AlGaAs LED's with metal mirrors.Wilkinson ST, Jokerst NM, Leavitt RP. Appl Opt. 1995 Dec 20. PMID: 21068949.