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Gerard Sanacora, MD, PhD, George D. and Esther S. Gross Professor of Psychiatry, spoke to The New York Times about the benefits and possible dangers associated with the use of ketamine to treat depression, suicidal ideation and chronic pain.

Greg Rhee, PhD, FACE, associate professor adjunct in psychiatry, is senior author of a paper in American Journal of Psychiatry that observed increasing trends of suicidal thoughts and suicide attempts among U.S. high school students from 2007 to 2021.

A genome-wide analyses in Nature Genetics identified 30 independent loci associated with obsessive–compulsive disorder, highlighting genetic overlap with other psychiatric disorders and implicating putative effector genes and cell types contributing to its etiology. Marco Galimberti, PhD, associate research scientist, is co-first author.

A new clinical trial launched by scientists at Yale School of Medicine and University of California San Francisco may offer hope to people with Parkinson’s disease who suffer from depression.

In a “taper,” patients encounter difficulties of two kinds: withdrawal, and the relapse of underlying conditions, explained Gerard Sanacora, MD, PhD, George D. and Esther S. Gross Professor of Psychiatry, and director of the Yale Depression Research Program, in a story in The New York Times.

Researchers, including first author Samuel Wilkinson, MD, associate professor of psychiatry, and senior author Greg Rhee, PhD, associate professor adjunct in psychiatry, wrote in JAMA Psychiatry about the need to conduct clinical trials to prevent suicide.

A new device acquired by Yale Interventional Psychiatry Service has dramatically reduced the amount of time patients have to sit while undergoing transcranial magnetic stimulation for major depressive disorder.

Patients are now being recruited for a study to compare the effectiveness of IV ketamine and esketamine nasal spray (otherwise known as Spravato) for people who suffer from treatment-resistant depression.

Gerard Sanacora, MD, PhD, George D. and Esther S. Gross Professor of Psychiatry, spoke to The New York Times about some common questions and misconceptions about antidepressants. Sanacora is director of the Yale Depression Research Program.