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Hongying Shen, PhD

Assistant Professor of Cellular and Molecular Physiology

Contact Information

Hongying Shen, PhD

Mailing Address

  • Cellular & Molecular Physiology

    ISTC building Rm120, 850 West Campus Drive , Yale West Campus

    West Haven, CT 06516

    United States



Hongying (Hoy) Shen is an assistant professor at Cellular & Molecular Physiology at Yale School of Medicine and Systems Biology Institute at Yale West Campus from Jan 2020. Dr. Shen is interested to use multidisciplinary approaches ranging from biochemistry, cell biology, genetics, molecular evolution, and metabolomics to study cellular metabolism underlying human health and diseases, which would ultimately offer new directions for diagnostics and therapeutics. Specifically, we will focus on the “deorphanization” of hundreds of enzymes and transporters of unknown functions that are encoded in the human genome and are important to cellular and organismal physiology.

Dr. Shen received her B.S. in chemistry from Nanjing University in China in 2006 and her Ph.D. in Molecular Biophysics and Biochemistry (MB&B) at Yale University in 2013, where she studied membrane curvature formation and lipid metabolism in endocytic trafficking in the laboratory of Dr. Pietro De Camilli at the cell biology department. She then completed her postdoctoral training with Dr. Vamsi Mootha at Massachusetts General Hospital and Harvard Medical School to develop integrated metabolomics and CRISPR screen approaches to study mitochondrial metabolism.

Education & Training

  • PhD
    Yale University, Molecular Biophysics and Biochemistry (2013)
  • BS
    Nanjing University, China, Chemistry (2006)

Honors & Recognition

AwardAwarding OrganizationDate
Rita Allen Foundation ScholarRita Allen Foundation2023
1907 Foundation Trailblazer Award in mental health1907 Foundation2022
Klingenstein-Simons Fellowship Award in NeurosciencesKlingenstein-Simons Foundation2021
Lois E. and Franklin H. Top, Jr., Yale Scholar AwardYale School of Medicine2021
Chan Zuckerberg Initiative Neurodegeneration Challenge Network Collaborative Pairs Pilot Project AwardsChan Zuckerberg Initiative2020
NIH Pathway to Independence Award (K99/R00)NIH2017
NIH NRSA Individual Postdoctoral Fellowship (F32)NIH2015
Mary Ellen Jones Dissertation PrizeYale University2013

Departments & Organizations