Chaopeng He
Postgraduate FellowAbout
Research
Publications
2025
Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss
Fu W, Chen M, Wang K, Chen Y, Cui Y, Xie Y, Lei Z, Hu W, Sun G, Huang G, He C, Fretz J, Hettinghouse A, Liu R, Cai X, Zhang M, Chen Y, Jiang N, He M, Wiznia D, Xu H, Chen Z, Chen L, Tang K, Zhou H, Liu C. Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss. Cell Research 2025, 35: 23-44. PMID: 39743632, PMCID: PMC11701132, DOI: 10.1038/s41422-024-01016-0.Peer-Reviewed Original ResearchConceptsGC-induced osteoporosisBone lossInflammatory arthritisAdverse effects of dexamethasoneGlucocorticoid-induced bone lossHigh-dose dexamethasoneEffect of dexamethasoneFDA-approved drug librarySynthetic GCTreat inflammatory arthritisImmunosuppressive drugsPrescribed anti-inflammatoryGC receptorCombinatorial administrationSide effectsLow affinityGlucocorticoidOsteoporosisDexamethasoneReceptorsAdverse effectsBinding receptorsAnti-inflammatoryDrug libraryTau deficiency
2022
The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis.
He CP, Chen C, Jiang XC, Li H, Zhu LX, Wang PX, Xiao T. The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis. Bone Joint Res 2022, 11: 292-300. PMID: 35549515, DOI: 10.1302/2046-3758.115.BJR-2021-0334.R1.Peer-Reviewed Original Research
2021
The function of lncRNAs in the pathogenesis of osteoarthritis.
He CP, Jiang XC, Chen C, Zhang HB, Cao WD, Wu Q, Ma C. The function of lncRNAs in the pathogenesis of osteoarthritis. Bone Joint Res 2021, 10: 122-133. PMID: 33560158, DOI: 10.1302/2046-3758.102.BJR-2020-0228.R1.Peer-Reviewed Original Research
Get In Touch
Contacts
Email