News for the Kliman Research Group

After most pregnancies, the placenta is thrown out, having done its job of nourishing and supporting the developing baby. But a new study raises the possibility that analyzing the placenta after birth may provide clues to a child’s risk for developing autism.

A substantial majority of miscarriages appear to be caused by genetic abnormalities rather than the usual suspects of thrombophilias, antiphospholipid syndromes, immunologic problems, or other maternal factors, study results suggest.

Harvey Kliman, MD, PhD, never planned on developing the first and only test that diagnoses autism risk at birth. "What I discovered was totally by accident," the research scientist in obstetrics, gynecology, and reproductive sciences at Yale School of Medicine, revealed. Dr. Kliman, lead author of a new study published in the journal Biological Psychiatry, examined placentas and found that abnormal folds (called trophoblast inclusions) could predict whether children had a higher risk of aut

A new study co-authored by a doctor from Yale New Haven Hospital suggests that a new tool could help predict who is at risk for autism at the time of birth. NBC’s Brian Williams reports.

A new find by Yale researchers may give parents a chance to learn if their child is at risk for autism at birth. The potential breakthrough would give doctors and parents a chance to intervene much earlier. Most children currently are not diagnosed until they are toddlers or school-aged.

Researchers now have a clearer understanding of a newborn's risk of developing an autism spectrum disorder. They discovered it starts with a genetic abnormality in the placenta.

A Test of the Uterine Lining Improves Chances of Success

The same proteins that mount a potent immune response to Zika viral infection can also harm the placenta and fetal development, according to a Yale-led study published in Science Immunology.

For some, every pregnancy ends in a loss within six weeks. “These particular patients always have losses and they are not infertile. They get pregnant easily but they always have these losses,” says Dr. Harvey Kliman, director of the Reproductive and Placental Research Unit in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine.