A Newly Identified Gene Ahed Plays Essential Roles in Murine Hematopoiesis through RNA Splicing
Nakai R, Yokota T, Tokunaga M, Takaishi M, Yokomizo T, Sudo T, Shi H, Yasumizu Y, Okuzaki D, Kokubu C, Tanaka S, Takaoka K, Yamanishi A, Yoshida J, Watanabe H, Kondoh G, Horie K, Hosen N, Sano S, Takeda J. A Newly Identified Gene Ahed Plays Essential Roles in Murine Hematopoiesis through RNA Splicing. Blood 2024, 144: 5614-5614. DOI: 10.1182/blood-2024-209978.Peer-Reviewed Original ResearchGene trap vectorUncharacterized genesRNA splicingDatabase of protein-protein interactionsConditional knockoutRegulation of RNA splicingHomozygous mutant clonesEmbryonic stem cellsDNA sequencing technologiesHematopoietic cellsFetal liverMutant embryonic stem cellsProtein-protein interactionsBloom's syndrome geneHematopoietic systemGene expression databaseDevelopment of hematopoietic cellsMouse ESC linesGenetic abnormalitiesMRNAs of genesEssential genesSequencing technologiesInterchromosomal recombinationTrap vectorUncharacterized function