Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn’s Disease Patients
Sekido Y, Yasumizu Y, Nishimura J, Kayama H, Matsuno H, Ogino T, Miyoshi N, Takahashi H, Haraguchi N, Hata T, Matsuda C, Doki Y, Mori M, Takeda K, Ohkura N, Sakaguchi S, Mizushima T. Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn’s Disease Patients. Digestion 2018, 99: 194-204. PMID: 30343293, DOI: 10.1159/000490890.Peer-Reviewed Original ResearchConceptsGene expression patternsGO BP termsExpression patternsGene OntologyGut homeostasisMyeloid cell subsetsInnate myeloid cellsBiological processesCrohn's diseaseComprehensive gene expression profilesMaintenance of gut homeostasisCell type-specific mechanismsCell subsetsMyeloid cellsHuman colonGene expression profilesHuman intestinal lamina propriaInnate immune responseLamina propriaType-specific mechanismsTranscriptional analysisGO-BPRNA sequencingDisease patientsPathogenesis of Crohn's disease