2002
Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury
Gardiner NJ, Cafferty WB, Slack SE, Thompson SW. Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury. Journal Of Neurochemistry 2002, 83: 100-109. PMID: 12358733, DOI: 10.1046/j.1471-4159.2002.01101.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CDAxotomyBlotting, WesternCell CompartmentationCell MembraneCell NucleusCytokine Receptor gp130CytoplasmDisease Models, AnimalGanglia, SpinalLeukemia Inhibitory Factor Receptor alpha SubunitMaleMembrane GlycoproteinsNeurons, AfferentPhenotypeProtein SubunitsRatsRats, WistarReceptors, CytokineReceptors, OSM-LIFSciatic NerveSciatic NeuropathyConceptsLeukemia inhibitory factor receptorDorsal root gangliaSensory neuronesNerve injuryAdult rat sensory neuronesSmall diameter sensory neuronesReceptor subunitsSensory neuropeptide CGRPSciatic nerve axotomyMale adult ratsIL-6 cytokinesExpression of gp130Rat sensory neuronesAdult nervous systemInhibitory factor receptorNeuropeptide CGRPIL-6 familyNerve axotomySignal-transducing receptor subunitInterleukin-6 familyRoot gangliaAdult sensory neuronesLevel of gp130Isolectin B4Adult rats
2001
Leukemia Inhibitory Factor Determines the Growth Status of Injured Adult Sensory Neurons
Cafferty W, Gardiner N, Gavazzi I, Powell J, McMahon S, Heath J, Munson J, Cohen J, Thompson S. Leukemia Inhibitory Factor Determines the Growth Status of Injured Adult Sensory Neurons. Journal Of Neuroscience 2001, 21: 7161-7170. PMID: 11549727, PMCID: PMC6762988, DOI: 10.1523/jneurosci.21-18-07161.2001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxotomyCalcitonin Gene-Related PeptideCell DivisionCell SurvivalCells, CulturedCytoprotectionFemaleGanglia, SpinalGrowth InhibitorsInjections, SpinalInterleukin-6Leukemia Inhibitory FactorLymphokinesMaleMiceMice, KnockoutNerve FibersNerve RegenerationNeuritesNeurons, AfferentPhenotypeRatsRats, WistarSciatic NerveTibial NerveConceptsLeukemia inhibitory factorLIF-/- miceAdult sensory neuronsSensory neuronsConditioning injuryInhibitory factorPeptidergic sensory neuronsMammalian sensory neuronsIntrinsic growth capacityExogenous leukemia inhibitory factorNerve damageReceptor antagonistNeuronsConditioning responseNeurite outgrowthInjuryGrowth statusVivoNormal regenerationStatusAntagonistGrowth capacityMice