2021
Altered hippocampal astroglial metabolism is associated with aging and preserved spatial learning and memory
Ebersole J, Rose G, Eid T, Behar K, Patrylo P. Altered hippocampal astroglial metabolism is associated with aging and preserved spatial learning and memory. Neurobiology Of Aging 2021, 102: 188-199. PMID: 33774381, DOI: 10.1016/j.neurobiolaging.2021.02.015.Peer-Reviewed Original ResearchConceptsArtificial cerebrospinal fluidAstroglial metabolismNeural metabolismHippocampus-dependent cognitive functionGlutamate-glutamine cyclingFischer 344 ratsHippocampus-dependent learningAge-related decreaseAU ratsCognitive functionLiquid chromatography-tandem mass spectroscopyGlutamatergic neurotransmissionCognitive declineHippocampal slicesSpatial learningCognitive statusHippocampal subregionsCerebrospinal fluidImpaired ratsMetabolism correlateYoung adultsCompensatory changesRatsC-glucoseMemory
1997
Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats
Bjorvatn B, Fagerland S, Eid T, Ursin R. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain Research 1997, 770: 81-88. PMID: 9372206, DOI: 10.1016/s0006-8993(97)00758-0.Peer-Reviewed Original ResearchConceptsDorsal raphe nucleusSlow-wave sleepRaphe nucleusSleep/Rapid eye movement (REM) sleepREM sleep increaseDeep slow wave sleepEye movement sleepArtificial cerebrospinal fluidMesopontine neuronsAutoreceptor stimulationReceptor agonistMovement sleepREM sleepCerebrospinal fluidWave sleepSleep increasesDPATPerfusionSleepAgonistsFourfold increaseBehavioral syndromeSyndromeNeurotransmission