2020
Increased connectivity in several bilateral frontal and fronto‐parietal networks predicts depressive symptoms in mid‐ to late‐life diabetics
Salardini A, Shen X, Hashemi‐Aghdam A, Laltoo E, Savoia S, Tokoglu F, Constable T. Increased connectivity in several bilateral frontal and fronto‐parietal networks predicts depressive symptoms in mid‐ to late‐life diabetics. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.043619.Peer-Reviewed Original ResearchDepressive symptomsBeck Depression InventoryDiabetic individualsBDI scoresDepression InventoryPrefrontal cortexBackground Depressive symptomsLate-life diabetesVascular cognitive impairmentDiagnosis of diabetesHigher BDI scoresComprehensive neuropsychological testingDorsal prefrontal cortexBilateral ventromedial prefrontal cortexRs-fMRI dataDiabetic patientsFazekas scoreMoCA scoresNeuropsychological testingFunctional connectivity matricesCognitive impairmentDepression symptomsVentromedial prefrontal cortexSymptomsRs-fMRI
2009
Pancreatic perfusion of healthy individuals and type 1 diabetic patients as assessed by magnetic resonance perfusion imaging
Hirshberg B, Qiu M, Cali AM, Sherwin R, Constable T, Calle RA, Tal MG. Pancreatic perfusion of healthy individuals and type 1 diabetic patients as assessed by magnetic resonance perfusion imaging. Diabetologia 2009, 52: 1561. PMID: 19488737, DOI: 10.1007/s00125-009-1406-8.Peer-Reviewed Original ResearchConceptsType 1 diabetic patientsPancreatic blood flowDiabetic patientsBlood flowIslet massHealthy volunteersPancreatic perfusionArterial spin labeling magnetic resonanceTotal pancreatic blood flowPancreatic beta-cell massConclusions/interpretationOur dataAims/hypothesisLossBeta-cell massMagnetic resonance perfusionSignificant differencesHuman pancreatic isletsDiabetes mellitusVascularised organsIslet functionMurine modelClamp studiesNormal volunteersHealthy individualsPatientsControl tissues