Nicotinic Antagonists Enhance Process Outgrowth by Rat Retinal Ganglion Cells in Culture
Lipton S, Frosch M, Phillips M, Tauck D, Aizenman E. Nicotinic Antagonists Enhance Process Outgrowth by Rat Retinal Ganglion Cells in Culture. Science 1988, 239: 1293-1296. PMID: 3344435, DOI: 10.1126/science.3344435.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsNicotinic antagonistsGanglion cellsFunctional nicotinic cholinergic receptorsRetinal ganglion cell processesRat retinal ganglion cellsRetinal ganglion cell neuronsNicotinic cholinergic drugsSpecific nicotinic antagonistsProcess outgrowthGanglion cell neuronsNicotinic cholinergic receptorsGanglion cell processesNormal control mechanismsApplied acetylcholinePostsynaptic effectsCholinergic receptorsAmacrine cellsCholinergic drugsPharmacologic blockadeSpontaneous leaksRemoval of inhibitionRetinal culturesAcetylcholineCell neurons