Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins.
Lipton S, Rasmussen H, Dowling J. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins. The Journal Of General Physiology 1977, 70: 771-791. PMID: 201724, PMCID: PMC2228513, DOI: 10.1085/jgp.70.6.771.Peer-Reviewed Original ResearchConceptsCombination of drugsIsolated toad retinaCyclic nucleotide levelsCombination of IBMXResponse amplitudeDrug levelsReceptor sensitivityLong-term exposureReceptor saturationIntracellular cGMPMM IBMXRetinaControl RingerSimilar alterationsElectrical activityCGMPRod photoreceptorsV-log IATPase pumpRod activitySuperfusionDark adaptationOuter segmentsSensitivity recoveryCyclic nucleotidesElectrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels.
Lipton S, Ostroy S, Dowling J. Electrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels. The Journal Of General Physiology 1977, 70: 747-770. PMID: 412914, PMCID: PMC2228514, DOI: 10.1085/jgp.70.6.747.Peer-Reviewed Original ResearchConceptsReceptor sensitivityLight-evoked responsesResponse amplitudeLow calcium RingerMembrane potential levelMembrane potentialExtracellular Ca2Intracellular storesAdapted rodRod sensitivityReceptor potentialElectrical activityRod photoreceptorsRinger's solutionV-log IRingerDark adaptationProlonged exposureSensitivity recoveryRetinaResponse saturationSubstantial depolarizationBufo marinus