Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120
Lipton S. Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120. Neuroreport 1992, 3: 913-915. PMID: 1421098, DOI: 10.1097/00001756-199210000-00023.Peer-Reviewed Original ResearchConceptsHIV envelope protein gp120Retinal ganglion cellsEnvelope protein gp120Neuronal injuryGanglion cellsGlial cellsProtein gp120N-methyl-D-aspartate antagonistsMixed neuronal-glial culturesRetinal ganglion cell neuronsNeuronal-glial culturesGanglion cell neuronsActivation of macrophagesPresence of macrophagesPM gp120Like damageGlial culturesCell neuronsGp120Early increaseFree calciumPostnatal retinaMacrophagesInjurious effectsNeurons