2000
How Are Neuronal Genes Expressed in Neurons? Regulation of NMDA Receptor Subunit Type 1 Gene as a Model
Okamoto S, Sherman K, Lipton S. How Are Neuronal Genes Expressed in Neurons? Regulation of NMDA Receptor Subunit Type 1 Gene as a Model. 2000, 355-360. DOI: 10.1007/978-4-431-66973-9_47.Peer-Reviewed Original ResearchType 1 geneRegulation of expressionGene regulationNeuronal genesEssential subunitDifferentiation proceedsTranscriptional levelFunctional NMDA receptorsNeuronal differentiationGenesVariety of moleculesNR1 geneNeuronal functionRegulationCentral nervous systemNR1ExpressionSynaptic responsesNMDA receptorsNeuronal activityNervous systemSubunitsNeuronsDifferentiationBest model
1986
Blockade of electrical activity promotes the death of mammalian retinal ganglion cells in culture.
Lipton S. Blockade of electrical activity promotes the death of mammalian retinal ganglion cells in culture. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 9774-9778. PMID: 3025849, PMCID: PMC387224, DOI: 10.1073/pnas.83.24.9774.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsNatural cell deathElectrical activityDeath of RGCsMammalian retinal ganglion cellsCell deathLevel of activityPostnatal day 2Spontaneous electrical activityElectrical blockadeIntraocular injectionMicroM tetrodotoxinPostnatal weekNeuronal activitySpontaneous activityTrophic factorsPostnatal ratsMammalian retinaDevelopment neuronsDay 2TetrodotoxinBlockadeIndividual neuronsAltered activity