Redox modulatory site of the NMDA receptor–channel complex: Regulation by oxidized glutathione
Sucher N, Lipton S. Redox modulatory site of the NMDA receptor–channel complex: Regulation by oxidized glutathione. Journal Of Neuroscience Research 1991, 30: 582-591. PMID: 1666131, DOI: 10.1002/jnr.490300316.Peer-Reviewed Original ResearchConceptsRedox modulatory siteNMDA receptor-channel complexReceptor-channel complexModulatory siteNMDA responsesFura-2 digital imagingRetinal ganglion cell neuronsWhole-cell current responsesPatch-clamp recording techniquesGanglion cell neuronsCo-agonist glycineIntracellular calcium concentrationCultures of ratNMDA subtypeNMDA receptorsGlutamate receptorsCell neuronsHigh extracellularExtracellular applicationComplete recoveryCalcium concentrationFurther decrementRecording techniquesPredominant actionNMDA