Ratio of S-nitrosohomocyst(e)ine to homocyst(e)ine or other thiols determines neurotoxicity in rat cerebrocortical cultures
D'Emilia D, Lipton S. Ratio of S-nitrosohomocyst(e)ine to homocyst(e)ine or other thiols determines neurotoxicity in rat cerebrocortical cultures. Neuroscience Letters 1999, 265: 103-106. PMID: 10327179, DOI: 10.1016/s0304-3940(99)00210-4.Peer-Reviewed Original ResearchConceptsN-methyl-D-aspartate agonistRat cerebrocortical culturesS-nitrosocysteineS-nitrosohomocysteineNeuronal degenerationCerebrocortical culturesS-nitrosothiolsSubsequent neurotoxicityAcute exposureDetermine outcomeNitric oxideForm peroxynitriteNeurotoxicityS-nitrosylationEndogenous O2S-nitrosoproteinsAgonists