Excitotoxins in Neuronal Apoptosis and Necrosis
Nicotera P, Lipton S. Excitotoxins in Neuronal Apoptosis and Necrosis. Cerebrovascular And Brain Metabolism Reviews 1999, 19: 583-591. PMID: 10366188, DOI: 10.1097/00004647-199906000-00001.Peer-Reviewed Original ResearchConceptsCommon histopathologic featuresLocal inflammatory reactionProgression of diseaseCell deathNeuronal injuryNeuronal lossHistopathologic featuresNeuronal demiseNeuropathologic conditionsInflammatory reactionNeurotoxic injuryNeuronal apoptosisPathologic conditionsNecrosisCell destructionPrevention of apoptosisNuclear pyknosisNeurodegenerative diseasesType of deathInjuryCell swellingGeneralized disruptionDeathApoptosisPrevalence