The neuropathogenesis of HIV-1 infection
Gendelman H, Lipton S, Tardieu M, Bukrinsky M, Nottet H. The neuropathogenesis of HIV-1 infection. Journal Of Leukocyte Biology 1994, 56: 389-398. PMID: 8083614, DOI: 10.1002/jlb.56.3.389.Peer-Reviewed Original ResearchConceptsCentral nervous system infectionHIV-1-infected macrophagesBrain tissue pathologyNervous system infectionHIV-1 infectionProductive viral replicationVirus-infected cellsHIV neuropathogenesisMononuclear phagocyte lineageSystem infectionHIV infectionNeuronal damageBrain macrophagesCNS diseaseGlial proliferationGiant cellsTissue pathologyViral replicationSoluble factorsNeurotoxic activityInfectionMacrophagesPhagocyte lineageHIVNeuropathogenesis