1997
Immunolocalization of the Na+–Ca2+ exchanger in mammalian myelinated axons
Steffensen I, Waxman S, Mills L, Stys P. Immunolocalization of the Na+–Ca2+ exchanger in mammalian myelinated axons. Brain Research 1997, 776: 1-9. PMID: 9439790, DOI: 10.1016/s0006-8993(97)00868-8.Peer-Reviewed Original ResearchConceptsOptic nerveSpinal cordDorsal root axonsSciatic nerve sectionRat optic nerveCentral myelinated axonsCardiac type IFiner processesSimilar staining patternNerve sectionDorsal columnsSciatic nerveFrozen cryostat sectionsAnoxic injuryAxonal profilesImmunofluorescence labeling techniqueMyelinated axonsCell bodiesCryostat sectionsImportant mediatorAxonal localizationMammalian axonsNerveAxonsStaining pattern
1994
Anoxic Injury of Central Myelinated Axons: Nonsynaptic Ionic Mechanisms
Ransom B, Waxman S, Stys P. Anoxic Injury of Central Myelinated Axons: Nonsynaptic Ionic Mechanisms. 1994, 77-90. DOI: 10.1007/978-3-642-78151-3_9.Peer-Reviewed Original ResearchGlial cellsAnoxic injuryWhite matterCentral nervous system traumaIrreversible anoxic injuryPathophysiology of strokeNervous system traumaCentral myelinated axonsNeuronal cell bodiesAnoxia/ischemiaGray matter areasCNS axonal injuryNeuronal injuryIonic mechanismsAxonal injurySystem traumaCell injuryMyelinated axonsInjuryCell bodiesAxonsMatter areasBrainMetabolic substratesReliable model system
1980
Absence of potassium conductance in central myelinated axons
Kocsis J, Waxman S. Absence of potassium conductance in central myelinated axons. Nature 1980, 287: 348-349. PMID: 7421994, DOI: 10.1038/287348a0.Peer-Reviewed Original ResearchConceptsCentral myelinated axonsMyelinated axonsAction potentialsPotassium conductanceDorsal column axonsVoltage-clamp experimentsLate outward currentOutward currentsAxonsSodium ion permeabilityLate increaseDepolarization phasePotassium permeabilityAxonal membraneRepolarizationMyelinInitial increaseVoltage-dependent changesSodium inactivationDemyelinationPrevious studies
1976
Morphology and physiology of visual callosal axons: evidence for a supernormal period in central myelinated axons
Waxman S, Swadlow H. Morphology and physiology of visual callosal axons: evidence for a supernormal period in central myelinated axons. Brain Research 1976, 113: 179-187. PMID: 953725, DOI: 10.1016/0006-8993(76)90017-2.Peer-Reviewed Original Research