2023
Machine learning-based prediction of clinical outcomes after first-ever ischemic stroke
Fast L, Temuulen U, Villringer K, Kufner A, Ali H, Siebert E, Huo S, Piper S, Sperber P, Liman T, Endres M, Ritter K. Machine learning-based prediction of clinical outcomes after first-ever ischemic stroke. Frontiers In Neurology 2023, 14: 1114360. PMID: 36895902, PMCID: PMC9990416, DOI: 10.3389/fneur.2023.1114360.Peer-Reviewed Original ResearchMini-Mental State ExaminationClinical outcomesBarthel IndexIschemic strokePrognostic factorsPatient dischargeCognitive functionFunctional recovery outcomesFurther patient careHealth Stroke ScaleEpidemiologic Studies Depression ScaleIschemic stroke patientsStroke ScaleAcute strokeProspective cohortRankin ScaleFunctional recoveryPrognostic featuresStroke patientsModified Telephone InterviewTreatment strategiesDepression ScaleIndividual patientsState ExaminationHealthcare providers
2021
The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the “Biomarkers and Perfusion—Training-Induced Changes After Stroke” (BAPTISe) Study
Jödicke R, Huo S, Kränkel N, Piper S, Ebinger M, Landmesser U, Flöel A, Endres M, Nave A. The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the “Biomarkers and Perfusion—Training-Induced Changes After Stroke” (BAPTISe) Study. Frontiers In Neurology 2021, 12: 731013. PMID: 34819906, PMCID: PMC8606784, DOI: 10.3389/fneur.2021.731013.Peer-Reviewed Original ResearchBarthel IndexFunctional outcomeCardiovascular eventsSubacute strokeExtracellular vesiclesSubacute ischemic stroke patientsLong-term cardiovascular outcomesWorse Barthel IndexIschemic stroke patientsLower Barthel IndexRecurrent cardiovascular eventsWorse functional outcomeSerial blood samplesLevels of EVsRegression analysisMixed-model regression analysisMixed model regression analysisCardiovascular outcomesIschemic strokeFluorescence-activated cellStroke patientsTrial interventionAerobic trainingClinical trialsLower increase
2020
Coagulation factor XII, XI, and VIII activity levels and secondary events after first ischemic stroke
Rohmann J, Huo S, Sperber P, Piper S, Rosendaal F, Heuschmann P, Endres M, Liman T, Siegerink B. Coagulation factor XII, XI, and VIII activity levels and secondary events after first ischemic stroke. Journal Of Thrombosis And Haemostasis 2020, 18: 3316-3324. PMID: 32935900, DOI: 10.1111/jth.15092.Peer-Reviewed Original ResearchConceptsFirst ischemic strokeIschemic strokeCoagulation factor XIIVascular outcomesHazard ratioRisk factorsActivity levelsFactor XIICox proportional hazards modelIschemic stroke eventsRecurrent vascular eventsWorse vascular outcomesCardiovascular risk factorsIschemic stroke patientsFirst thrombotic eventSecondary eventsProportional hazards modelModerate ischemic stroke patientsFactor activity levelsRecurrent strokeCause mortalityProspective cohortVascular eventsThrombotic eventsStroke events