2021
The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the “Biomarkers and Perfusion—Training-Induced Changes After Stroke” (BAPTISe) Study
Jödicke R, Huo S, Kränkel N, Piper S, Ebinger M, Landmesser U, Flöel A, Endres M, Nave A. The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the “Biomarkers and Perfusion—Training-Induced Changes After Stroke” (BAPTISe) Study. Frontiers In Neurology 2021, 12: 731013. PMID: 34819906, PMCID: PMC8606784, DOI: 10.3389/fneur.2021.731013.Peer-Reviewed Original ResearchBarthel IndexFunctional outcomeCardiovascular eventsSubacute strokeExtracellular vesiclesSubacute ischemic stroke patientsLong-term cardiovascular outcomesWorse Barthel IndexIschemic stroke patientsLower Barthel IndexRecurrent cardiovascular eventsWorse functional outcomeSerial blood samplesLevels of EVsRegression analysisMixed-model regression analysisMixed model regression analysisCardiovascular outcomesIschemic strokeFluorescence-activated cellStroke patientsTrial interventionAerobic trainingClinical trialsLower increase
2019
Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B)
Sperber P, Siegerink B, Huo S, Rohmann J, Piper S, Prüss H, Heuschmann P, Endres M, Liman T. Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B). Stroke 2019, 50: 3213-3219. PMID: 31526121, DOI: 10.1161/strokeaha.119.026100.Peer-Reviewed Original ResearchConceptsSecondary vascular eventsFunctional outcomeVascular eventsHigh titersNMDAR1-ABSeronegative patientsSeropositive patientsFirst strokeLong-term clinical outcomesLong-term functional outcomeCombined end pointRecurrent vascular eventsOutcomes of patientsPoor functional outcomeSub-group analysisOutcomes of interestAnti-NMDAAutoimmune encephalitisCardiovascular riskProspective cohortRankin ScaleHazard ratioClinical outcomesNeuroprotective effectsReceptor antibodies