1995
Genesis of the retinal pigment epithelium in the macaque monkey
Rapaport D, Rakic P, Yasamura D, LaVail M. Genesis of the retinal pigment epithelium in the macaque monkey. The Journal Of Comparative Neurology 1995, 363: 359-376. PMID: 8847405, DOI: 10.1002/cne.903630303.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyCell DifferentiationFemaleMacaca mulattaPigment Epithelium of EyePregnancyRetinaThymidineConceptsRetinal pigment epitheliumCell genesisRPE cellsPeripheral retinaRadiolabelled cellsPigment epitheliumRhesus monkey fetusesCells/Embryonic day 25Time of birthMonkey fetusesCentral retinaPostnatal monthPostnatal periodLabeling indexDay 204Macaque monkeysDay 25RetinaJuvenile retinaOptic cupEpitheliumHigh rateNeuroretinaLast cellNeurotransmitter receptors in the proliferative zones of the developing primate occipital lobe
Lidow M, Rakic P. Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe. The Journal Of Comparative Neurology 1995, 360: 393-402. PMID: 8543647, DOI: 10.1002/cne.903600303.Peer-Reviewed Original ResearchConceptsCortical neuronsOccipital lobeReceptor subtypesSubventricular zoneHigh-affinity kainate receptorsProliferative zoneSubventricular proliferative zonesNeurotransmitter receptor subtypesCell proliferationEmbryonic cerebral wallGamma-aminobutyric acidD1 dopaminergicMonkey fetusesDeep laminaeKainate receptorsNeuronal productionCerebral wallMultiple neurotransmittersCortical neurogenesisNeurotransmitter receptorsVisual cortexFetusesNeuronsAlpha 1Alpha 2
1994
Unique profiles of the alpha 1-, alpha 2-, and beta-adrenergic receptors in the developing cortical plate and transient embryonic zones of the rhesus monkey
Lidow, Rakic P. Unique profiles of the alpha 1-, alpha 2-, and beta-adrenergic receptors in the developing cortical plate and transient embryonic zones of the rhesus monkey. Journal Of Neuroscience 1994, 14: 4064-4078. PMID: 8027763, PMCID: PMC6577033, DOI: 10.1523/jneurosci.14-07-04064.1994.Peer-Reviewed Original ResearchConceptsTransient embryonic zonesBeta-adrenergic receptorsCortical plateAdrenergic receptor subtypesSubplate zoneReceptor subtypesCerebral wallRhesus monkeysAlpha 1Alpha 1 sitesAlpha 2Alpha 2 receptorsAlpha 1 receptorsEmbryonic zonesIntensive proliferative activityReceptor autoradiographyCortical neuronsSubventricular zoneCortical developmentOccipital lobeBeta receptorsAdrenergic receptorsAdrenergic sitesVisual cortexGerminal zoneEarly neurogenesis in the anterior hypothalamus of the rhesus monkey
van Eerdenburg F, Rakic P. Early neurogenesis in the anterior hypothalamus of the rhesus monkey. Brain Research 1994, 79: 290-296. PMID: 7955328, DOI: 10.1016/0165-3806(94)90134-1.Peer-Reviewed Original ResearchConceptsAnterior hypothalamusRhesus monkeysNeurogenetic gradientsPrimate hypothalamusParaventricular nucleusGestational periodVentral gradientSupraoptic nucleusMonkey neuronsHypothalamusNeuronal generationNeuronsEarly neurogenesisSpecific nucleiNeurogenesisMonkeysEarly stagesSpecific differencesGestationNucleusWeeks
1992
Scheduling of Monoaminergic Neurotransmitter Receptor Expression in the Primate Neocortex during Postnatal Development
Lidow M, Rakic P. Scheduling of Monoaminergic Neurotransmitter Receptor Expression in the Primate Neocortex during Postnatal Development. Cerebral Cortex 1992, 2: 401-416. PMID: 1330122, DOI: 10.1093/cercor/2.5.401.Peer-Reviewed Original ResearchConceptsMonoaminergic receptorsCortical layersReceptor densityCytoarchitectonic areasPostnatal developmentNeurotransmitter receptor expressionSuperficial cortical layersMonths of ageTime of pubertyCerebral cortexCortical maturationPostnatal monthReceptor expressionPrimary motorPrimate neocortexVisual cortexRhesus monkeysFourth monthReceptorsMonthsReceptor sitesCortexDevelopmental changesDevelopmental courseTransient overproductionNeurogenesis of the amygdaloid nuclear complex in the Rhesus monkey
Kordower J, Piecinski P, Rakic P. Neurogenesis of the amygdaloid nuclear complex in the Rhesus monkey. Brain Research 1992, 68: 9-15. PMID: 1521327, DOI: 10.1016/0165-3806(92)90242-o.Peer-Reviewed Original ResearchConceptsAmygdaloid complexRhesus monkeysAmygdaloid nucleusEmbryonic day 27Early postmitotic neuronsEarly postnatal periodAmygdaloid nuclear complexPregnant monkeysDays gestationPostnatal periodTemporal lobeVentral gradientDay 27Postmitotic neuronsNeurogenesisFirst neuronsNeuronsThymidine autoradiographyPrimate developmentMonkeysGestationNuclear complexTime coursePatterns of connectivityNeuroanatomical subdivisions
1991
Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex.
Lidow M, Goldman-Rakic P, Rakic P. Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 10218-10221. PMID: 1658799, PMCID: PMC52899, DOI: 10.1073/pnas.88.22.10218.Peer-Reviewed Original ResearchCytogenesis in the monkey retina
la Vail M, Rapaport D, Rakic P. Cytogenesis in the monkey retina. The Journal Of Comparative Neurology 1991, 309: 86-114. PMID: 1894769, DOI: 10.1002/cne.903090107.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsAutoradiographyDNA ReplicationGestational AgeMacacaRetinaRetinal Ganglion CellsThymidineTritium
1990
Autoradiographic comparison of D1-specific binding of [3H]SCH39166 and SCH23390 in the primate cerebral cortex
Lidow M, Goldman-Rakic P, Rakic P, Gallager D. Autoradiographic comparison of D1-specific binding of [3H]SCH39166 and SCH23390 in the primate cerebral cortex. Brain Research 1990, 537: 349-354. PMID: 2085785, DOI: 10.1016/0006-8993(90)90384-n.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyBenzazepinesCerebral CortexDopamine AntagonistsFlupenthixolMacaca mulattaReceptors, DopamineConceptsPrimate cerebral cortexCis-flupentixolCerebral cortexNovel dopamine D1 receptor antagonistDopamine D1 receptor antagonistD1 receptor antagonistSpecific bindingD1 receptor subtypeMicroM SCH23390Receptor antagonistReceptor subtypesAutoradiographic comparisonOccipital cortexLaminar patternQuantitative autoradiographySCH23390CortexRadioligandHigh affinityNon-specific bindingAntagonistSCH39166AgentsSubtypesReceptorsNeurogenesis of the magnocellular basal forebrain nuclei in the rhesus monkey
Kordower J, Rakic P. Neurogenesis of the magnocellular basal forebrain nuclei in the rhesus monkey. The Journal Of Comparative Neurology 1990, 291: 637-653. PMID: 2329194, DOI: 10.1002/cne.902910410.Peer-Reviewed Original ResearchConceptsBasal forebrain nucleiMagnocellular basal forebrain nucleiBasal forebrainForebrain nucleiRhesus monkeysAnterior basal forebrainEmbryonic day 27Early postnatal periodPeak of neurogenesisCortical-cortical connectionsNucleus basalisNeurogenic gradientCortical neuronsDays gestationMagnocellular neuronsPostnatal periodTarget neuronsNeuronal genesisCortical mantleMagnocellular nucleusPregnant animalsDay 27Intermediate divisionGestationPosterior division
1989
Quantitative autoradiographic mapping of serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in the neocortex of the rhesus monkey
Lidow M, Goldman‐Rakic P, Gallager D, Rakic P. Quantitative autoradiographic mapping of serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in the neocortex of the rhesus monkey. The Journal Of Comparative Neurology 1989, 280: 27-42. PMID: 2918094, DOI: 10.1002/cne.902800104.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyCerebral CortexCitalopramFemaleKetanserinMacacaMacaca mulattaMaleReceptors, SerotoninConceptsLayer IIIReceptor subtypesUptake sitesCortical areasVisual cortexLayer IRhesus monkeysPrimary motor cortexSerotonin uptake sitesQuantitative autoradiographic mappingMonkey cerebral cortexDistribution of serotoninPrimary visual cortexPattern of distributionIVC betaAutoradiographic mappingCerebral cortexMotor cortexLayer IVCortical functionOccipital lobePrimary motorPrestriate cortexReceptor distributionCortex
1988
Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex
Rakic P, Goldman-Rakic P, Gallager D. Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex. Journal Of Neuroscience 1988, 8: 3670-3690. PMID: 2848104, PMCID: PMC6569589, DOI: 10.1523/jneurosci.08-10-03670.1988.Peer-Reviewed Original ResearchConceptsMajor neurotransmitter receptorsArea 17Neurotransmitter receptorsBmax valuesQuinuclidinyl benzilateCortical layersVisual cortical areasAdult rhesus monkeysExtrinsic afferentsCholinergic receptorsCell-packing densityQuantitative autoradiographyCortical areasLaminar patternSpecific laminaeMonkey striateAdult monkeysArea 18Cytoarchitectonic areasEndogenous neurotransmittersLayer IRhesus monkeysBenzilateAlpha 2ReceptorsDifferential quenching and limits of resolution in autoradiograms of brain tissue labeled with3H-,125I- and14C-compounds
Lidow M, Goldman-Rakic P, Rakic P, Gallager D. Differential quenching and limits of resolution in autoradiograms of brain tissue labeled with3H-,125I- and14C-compounds. Brain Research 1988, 459: 105-119. PMID: 3167570, DOI: 10.1016/0006-8993(88)90290-9.Peer-Reviewed Original ResearchConceptsBrain sectionsAdult monkeysBrain tissuePrimary motor cortexPrimary visual cortexAutoradiograms of sectionsAdult rhesus monkeysMotor cortexCortical sectionsLaminar patternLayer IIIPrimate brainVisual cortexRhesus monkeysBrain structuresNeocortexCortexSignificant attenuationAutoradiographic measurementFilm autoradiographyMonkeysAutoradiogramsNature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey
Eckenhoff M, Rakic P. Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey. Journal Of Neuroscience 1988, 8: 2729-2747. PMID: 3411351, PMCID: PMC6569394, DOI: 10.1523/jneurosci.08-08-02729.1988.Peer-Reviewed Original ResearchConceptsProliferative cellsMitotic divisionPostmitotic cellsUltra-structural characteristicsPossible functionsElectron microscopic levelStable populationGlial fibrillary acidic proteinNeuronal cellsStem cellsJuvenile periodMajor classesMature primatesSubgranular zoneDentate gyrusGlial cellsLife spanCellsGFAP-negative cellsFateRhesus monkeysAcidic proteinNew neuronsPostpubertal animalsFibrillary acidic protein
1985
DNA Synthesis and Cell Division in the Adult Primate Braina
RAKIC P. DNA Synthesis and Cell Division in the Adult Primate Braina. Annals Of The New York Academy Of Sciences 1985, 457: 193-211. PMID: 3913364, DOI: 10.1111/j.1749-6632.1985.tb20806.x.Peer-Reviewed Original ResearchConceptsPostembryonic neurogenesisNonmammalian vertebratesCell divisionDNA precursorsPrimate central nervous systemStable populationDNA synthesisNonprimate mammalsCentral nervous systemMature primatesNeuronal additionGlial cellsNervous systemAdult monkeysRetention of memoryAutoradiographic analysisMultiple injectionsVertebratesDevelopmental periodMammalsVariable degreesNeuronsJuvenilesNeurogenesisTurnoverLimits of Neurogenesis in Primates
Rakic P. Limits of Neurogenesis in Primates. Science 1985, 227: 1054-1056. PMID: 3975601, DOI: 10.1126/science.3975601.Peer-Reviewed Original Research
1981
Neurogenetic gradients in the superior and inferior colliculi of the rhesus monkey
Cooper M, Rakic P. Neurogenetic gradients in the superior and inferior colliculi of the rhesus monkey. The Journal Of Comparative Neurology 1981, 202: 309-334. PMID: 7298901, DOI: 10.1002/cne.902020303.Peer-Reviewed Original ResearchConceptsSuperior colliculusInferior colliculusCentral nucleusInferior colliculiRhesus monkeysVentrodorsal gradientLateral-medial gradientAnterior-posterior gradientTectal neuronsNeurogenetic gradientsPeak proliferationSubventricular zoneSelective cell deathRostrocaudal gradientCNS cellsFinal mitosisNeuronsDistinctive spatiotemporal patternsNeurogenesisEmbryonic dayColliculiColliculusGestation periodCell deathLateral cell movementThe total number, time of origin and kinetics of proliferation of neurons comprising the deep cerebellar nuclei in the rhesus monkey
Gould B, Rakic P. The total number, time of origin and kinetics of proliferation of neurons comprising the deep cerebellar nuclei in the rhesus monkey. Experimental Brain Research 1981, 44: 195-206. PMID: 7286107, DOI: 10.1007/bf00237341.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsAutoradiographyCell CountCell DivisionCerebellar NucleiFetusMacaca mulattaNeuronsThymidineConceptsCerebellar nucleiPosterior interposed nucleusDeep nucleiSmall neuronsDentate nucleusFastigial nucleusRhesus monkeysInterposed nucleusCessation of neurogenesisGenesis of neuronsPostnatal rhesus monkeysIntermediate time courseDay gestation periodDeep cerebellar nucleiPostnatal ageCerebellar cortexAxonal connectionsOld monkeysNeuron populationsKinetics of proliferationNeuronsAutoradiographic methodTotal numberNeurogenesisPeak of proliferationThe prenatal development of the pulvinar in the monkey: 3H-thymidine autoradiographic and morphometric analyses
Ogren M, Rakic P. The prenatal development of the pulvinar in the monkey: 3H-thymidine autoradiographic and morphometric analyses. Brain Structure And Function 1981, 162: 1-20. PMID: 7283168, DOI: 10.1007/bf00318090.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyBiometryCell MovementDiencephalonMacacaMacaca mulattaNeuronsThalamic NucleiThalamusTime FactorsConceptsPulvinar neuronsSubpopulation of neuronsAdjacent thalamic nucleiThirds of gestationMorphometric analysisSite of originSeries of animalsLateral pulvinarAfferent inputMedial pulvinarThalamic nucleiSubventricular zoneTelencephalic originThird ventricleLateral aspectCytoarchitectonic boundariesHuman pulvinarPulvinarNeuronsEmbryonic dayThymidine autoradiographyPrenatal developmentHistological sectionsMonkeysGestationThe genesis of efferent connections from the visual cortex of the fetal rhesus monkey
Shatz C, Rakic P. The genesis of efferent connections from the visual cortex of the fetal rhesus monkey. The Journal Of Comparative Neurology 1981, 196: 287-307. PMID: 7217358, DOI: 10.1002/cne.901960208.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusInfragranular cortical layersFetal rhesus monkeysSuperior colliculusRhesus monkeysCortical projectionsPyramidal neuronsVisual cortexCortical layersSubcortical structuresDorsal lateral geniculate nucleusTopographic orderCell-poor zoneCorticogeniculate projectionsSuperficial grayAfferent pathwaysCortical efferentsCortical injectionsEfferent pathwaysCortical plateDendritic arborizationArea 17Pyramidal cellsEfferent connectionsGeniculate nucleus