2022
Neural Stem Cells in Adult Mammals are not Astrocytes
Velloso F, Shankar S, Parpura V, Rakic P, Levison S. Neural Stem Cells in Adult Mammals are not Astrocytes. ASN Neuro 2022, 14: 17590914221134739. PMID: 36330653, PMCID: PMC9638700, DOI: 10.1177/17590914221134739.Peer-Reviewed Original ResearchConceptsAdult mammalian subventricular zoneNeural stem cellsMammalian subventricular zoneMammalian neural stem cellsComparative transcriptomic analysisDistinct gene expression profilesStem cellsAdult mammalian neural stem cellsGene expression profilesSingle-cell RNAseqFunction of NSCsMurine neural stem cellsSubventricular zoneTranscriptomic analysisExpression profilesAdult murine neural stem cellsCell sortingAdult mammalsFunction of astrocytesCellsNew neuronsSubtypes of astrocytesMammalsRNAseqNiche
2000
From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model
Rakic P. From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model. Results And Problems In Cell Differentiation 2000, 30: 1-19. PMID: 10857183, DOI: 10.1007/978-3-540-48002-0_1.Peer-Reviewed Original ResearchConceptsEssential model systemMosaic animalsLarge brain sizeSmall invertebratesGenome sequenceMolecular geneticsInduced mutationsVersatile animal modelArea of neurobiologyNormal developmentNeurological mutationDevelopmental neurobiologyBrain sizeModel systemMutationsMouse modelCongenital malformationsAnimal modelsNervous systemHuman nervous systemExperimental neuropathologyInvertebratesNonhuman primatesMammalsGenetics
1985
DNA Synthesis and Cell Division in the Adult Primate Braina
RAKIC P. DNA Synthesis and Cell Division in the Adult Primate Braina. Annals Of The New York Academy Of Sciences 1985, 457: 193-211. PMID: 3913364, DOI: 10.1111/j.1749-6632.1985.tb20806.x.Peer-Reviewed Original ResearchConceptsPostembryonic neurogenesisNonmammalian vertebratesCell divisionDNA precursorsPrimate central nervous systemStable populationDNA synthesisNonprimate mammalsCentral nervous systemMature primatesNeuronal additionGlial cellsNervous systemAdult monkeysRetention of memoryAutoradiographic analysisMultiple injectionsVertebratesDevelopmental periodMammalsVariable degreesNeuronsJuvenilesNeurogenesisTurnover