2007
4.14 The Development and Evolutionary Expansion of the Cerebral Cortex in Primates
Rakic P, Kornack D. 4.14 The Development and Evolutionary Expansion of the Cerebral Cortex in Primates. 2007, 243-259. DOI: 10.1016/b0-12-370878-8/00004-5.Peer-Reviewed Original ResearchEvolutionary expansionSpecies-specific sizeSmall genetic differencesCerebral cortexEvolutionary mechanismsMammalian speciesBrain evolutionCell cycleCellular eventsSpontaneous mutationsGenetic differencesRadial unit hypothesisRodent embryosBasic organizationModern neurobiologyEmbryosNew insightsNon-human primatesCorticogenesisHuman uniquenessBiological substratesCortexNeuronal interactionsEmbryogenesisHuman cerebrum
2000
Radial Unit Hypothesis of Neocortical Expansion
Rakic P. Radial Unit Hypothesis of Neocortical Expansion. Novartis Foundation Symposia 2000, 228: 30-45. PMID: 10929315, DOI: 10.1002/0470846631.ch3.Peer-Reviewed Original ResearchConceptsRadial unit hypothesisSpecies-specific sizeFamily of genesMutations of genesVentricular zoneMammalian evolutionFounder cellsNatural selectionRegulatory genesCell divisionMorphoregulatory moleculesPostmitotic cellsTransgenic animalsCortical plateCell deathNeocortical expansionGenesBasic organizationGlial scaffoldingColumnar unitsCortical cellsCerebral cortexCellsCortical developmentSynaptic connections