2024
Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization
Zhang Z, Pu Y, Yu L, Bai H, Duan W, Liu X, Nie X, Wen Z, Zheng L, Hu X, Leng X, Pan Y, Petersen N, Liu L. Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization. Journal Of The American Heart Association 2024, 13: e033633. PMID: 38533955, PMCID: PMC11179781, DOI: 10.1161/jaha.123.033633.Peer-Reviewed Original ResearchConceptsBlood pressure targetsBlood pressureAutoregulatory limitsWorse outcomesAssociated with symptomatic intracranial hemorrhageAssociated with unfavorable clinical outcomesPressure targetsAssociated with worse outcomesAssociated with poor outcomesSignificant infarction growthSymptomatic intracranial hemorrhageUnfavorable clinical outcomeLarge vessel occlusion strokeAcute ischemic strokeMean velocity indexIntracranial hemorrhageBP management strategiesNeurological deteriorationClinical outcomesInfarct growthPoor outcomeEndovascular thrombectomyOcclusion strokeRecanalizationIschemic strokeRadiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke
Avery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.Peer-Reviewed Original ResearchCollateral statusCollateral scoreLarge vessel occlusionAcute LVO strokeRadiomics modelTest cohortCT angiography of patientsAdmission computed tomography angiographyAnterior circulation territoryAngiography of patientsLong-term outcomesReceiver operating characteristic areaRadiomics-based predictionCollateral arterial circulationOperating characteristics areaAdmission CTACirculation territoryCT angiographyClinical outcomesRadiomic featuresTreatment triageOcclusion strokeVessel occlusionPatientsArterial circulation
2022
Stroke Severity and Early Ischemic Changes Predict Infarct Growth Rate and Clinical Outcomes in Patients With Large‐Vessel Occlusion
Quispe‐Orozco D, Sequeiros J, Farooqui M, Zevallos C, Mendez‐Ruiz A, Dajles A, Kobsa J, Prasad A, Petersen N, Ortega‐Gutierrez S. Stroke Severity and Early Ischemic Changes Predict Infarct Growth Rate and Clinical Outcomes in Patients With Large‐Vessel Occlusion. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000182.Peer-Reviewed Original ResearchAlberta Stroke Program Early CT ScoreHealth Stroke Scale scoreStroke Scale scoreEarly ischemic changesFast progressorsScale scoreSuccessful reperfusionStroke severityEndovascular therapyIschemic changesClinical outcomesNational InstituteAnterior circulation large vessel occlusion strokeRetrospective cohort observational studyLarge vessel occlusion strokeInfarct growth ratesComprehensive stroke centerHealth Stroke ScaleCohort observational studyFinal infarct volumeLarge vessel occlusionMultivariate logistic regressionIschemic stroke progressionYouden's J indexInfarct progression
2021
Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome
Nogueira R, Aries M, Minhas J, Petersen N, Xiong L, Kainerstorfer J, Castro P. Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome. Cerebrovascular And Brain Metabolism Reviews 2021, 42: 430-453. PMID: 34515547, PMCID: PMC8985432, DOI: 10.1177/0271678x211045222.Peer-Reviewed Original ResearchConceptsDynamic cerebral autoregulationAcute phaseClinical outcomesCerebral autoregulationAcute ischemic strokeCerebral hemodynamic parametersPotential therapeutic targetCerebrovascular disease statesAcute strokeIschemic strokeStroke onsetCerebral perfusionCerebral circulationIntracerebral hemorrhageHigh morbidityHemodynamic parametersIndividual patientsPerfusion interventionsNew therapiesTherapeutic targetHemodynamic aspectsPatientsAdditional treatmentDisease statesRelevant studies
2019
Association of Personalized Blood Pressure Targets With Hemorrhagic Transformation and Functional Outcome After Endovascular Stroke Therapy
Petersen NH, Silverman A, Wang A, Strander S, Kodali S, Matouk C, Sheth KN. Association of Personalized Blood Pressure Targets With Hemorrhagic Transformation and Functional Outcome After Endovascular Stroke Therapy. JAMA Neurology 2019, 76: 1256-1258. PMID: 31355872, PMCID: PMC6664391, DOI: 10.1001/jamaneurol.2019.2120.Peer-Reviewed Original Research