2019
Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage. Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.Peer-Reviewed Original ResearchConceptsLimits of autoregulationAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageFunctional outcomeArterial pressureIntracranial pressureBP targetsWorse outcomesPercent timeBlood pressure targetsBlood pressure managementMean arterial pressureModified Rankin ScalePotential neuroprotective strategiesWorse functional outcomePoor functional outcomeCerebral blood flowMultivariate logistic regressionTotal monitoring periodAutoregulatory indexPressure targetsCerebral ischemiaNeuroprotective strategiesRankin ScaleCerebral autoregulationChanges on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage
Ortega-Gutierrez S, Samaniego E, Reccius A, Huang A, Zheng-Lin B, Masukar A, Marshall R, Petersen N. Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2019, 127: 149-153. PMID: 31407076, DOI: 10.1007/978-3-030-04615-6_22.Peer-Reviewed Original ResearchConceptsDynamic cerebral autoregulationAneurysmal subarachnoid hemorrhageCerebral blood flow velocityBlood pressureSymptomatic vasospasmCerebral ischemiaSAH patientsCerebral autoregulationSubarachnoid hemorrhageCerebral blood flow regulationGlasgow Coma ScoreSystemic blood pressureDelayed Cerebral IschemiaLarge cohort studyBlood flow regulationBlood flow velocityRecording periodDCA assessmentCohort studyComa ScoreEntire recording periodSymptom onsetMedian timeDay 3Early identification
2017
Multimodality Monitoring
Cassa R, Petersen N. Multimodality Monitoring. 2017, 363-385. DOI: 10.1007/978-3-319-48669-7_20.Peer-Reviewed Original ResearchMultimodality monitoringBrain injuryJugular venous oxygen saturationAdditional brain injuryBrain tissue hypoxiaAcute brain injuryNon-convulsive seizuresVenous oxygen saturationBrain tissue oxygenationCerebral blood flowCerebral microdialysisQuantitative EEG measuresCerebral ischemiaIntracranial hypertensionSubclinical changesDelivery of oxygenVulnerable brainTissue hypoxiaIntracranial pressureOxygen saturationPathologic eventsBlood flowTissue oxygenationPhysiologic parametersMetabolic changes
2012
Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage (P06.257)
Ortega-Gutierrez S, Petersen N, Reccius A, Huang A, Linares-Tapia G, Marshall R, Badjatia N. Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage (P06.257). Neurology 2012, 78: p06.257-p06.257. DOI: 10.1212/wnl.78.1_meetingabstracts.p06.257.Peer-Reviewed Original Research