2010
Chapter 331 IRS-Protein Scaffolds and Insulin/IGF Action in Central and Peripheral Tissues
White M. Chapter 331 IRS-Protein Scaffolds and Insulin/IGF Action in Central and Peripheral Tissues. 2010, 2873-2883. DOI: 10.1016/b978-0-12-374145-5.00331-4.Peer-Reviewed Original ResearchInsulin-like growth factor signalsInsulin-like receptorGrowth factor signalsΒ-cell growthIRS proteinsNutrient homeostasisFactor signalsAdapter moleculeSystemic growthInsulin receptorSimilar signalingInsulin targetsRational platformCommon systemic disordersType 2 diabetesCascadePhysiologic roleInsulin actionInsulin resistanceSystemic disordersIGF actionInsulin responseInsulin secretionCardiovascular diseaseDiabetic tissues
2006
Regulating insulin signaling and -cell function through IRS proteinsThis paper is one of a selection of papers published in this Special Issue, entitled Second Messengers and Phosphoproteins12th International Conference.
White M. Regulating insulin signaling and -cell function through IRS proteinsThis paper is one of a selection of papers published in this Special Issue, entitled Second Messengers and Phosphoproteins12th International Conference. Canadian Journal Of Physiology And Pharmacology 2006, 84: 725-737. PMID: 16998536, DOI: 10.1139/y06-008.Peer-Reviewed Original ResearchConceptsType 2 diabetesInsulin resistanceBeta-cell destructionPeripheral insulin resistanceDiabetes mellitusChronic hyperglycemiaSystemic disordersFemale infertilityInsulin secretionCardiovascular diseaseCell functionInevitable progressionComplex disorderDisordersDiabetesGreater frequencyPrevalent formInsulinPhosphoproteins12th International ConferenceAgeSecond messengerDyslipidemiaHypertensionMellitusAutoimmune