1978
Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism
Cedarbaum J, Aghajanian G. Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism. Life Sciences 1978, 23: 1383-1392. PMID: 214648, DOI: 10.1016/0024-3205(78)90398-3.Peer-Reviewed Original ResearchConceptsLocus coeruleusNerve stimulationLocus coeruleus neuronsRat locus coeruleusPeripheral nerve stimulationBursts of spikesNeuronal responsivityNoradrenergic neuronsCoeruleus neuronsAntidromic activationAxon collateralsAdrenergic antagonistsPutative transmittersNoxious stimuliPeripheral stimuliUnit firingReduced responsivityAutoinhibitory actionInhibitory mechanismPiperoxaneNeuronsAdditional stimulusStimulationCollateralsStimuliAfferent projections to the rat locus coeruleus as determined by a retrograde tracing technique
Cedarbaum J, Aghajanian G. Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique. The Journal Of Comparative Neurology 1978, 178: 1-15. PMID: 632368, DOI: 10.1002/cne.901780102.Peer-Reviewed Original ResearchConceptsLocus coeruleusRat locus coeruleusCentral gray substanceLateral hypothalamic areaRetrograde tracing techniquesLateral reticular nucleusCatecholamine cell groups A1Magnocellular preoptic areaSingle-cell recordingsDorsal hornReactive neuronsNoradrenergic neuronsSolitary tractAfferent innervationLabeled neuronsHypothalamic areaReticular nucleusHRP injectionsPreoptic areaSpinal cordInsular cortexAfferent projectionsGray substanceReticular formationAfferent connections
1977
Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons
Aghajanian GK, Cedarbaum JM, Wang RY. Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons. Brain Research 1977, 136: 570-577. PMID: 922502, DOI: 10.1016/0006-8993(77)90083-x.Peer-Reviewed Original Research