2000
Voltage-Gated Calcium Currents in Axotomized Adult Rat Cutaneous Afferent Neurons
Baccei M, Kocsis J. Voltage-Gated Calcium Currents in Axotomized Adult Rat Cutaneous Afferent Neurons. Journal Of Neurophysiology 2000, 83: 2227-2238. PMID: 10758131, DOI: 10.1152/jn.2000.83.4.2227.Peer-Reviewed Original ResearchConceptsVoltage-gated calcium currentsCutaneous afferent neuronsPA/pFNerve injuryCutaneous afferentsType 1 cellsBarium currentsAfferent neuronsHVA currentsCalcium currentLow threshold T-type currentWhole-cell patch-clamp techniqueDorsal root ganglion neuronsCell patch-clamp techniqueFluoro-Gold labelingOmega-agatoxin TKSciatic nerve injuryOmega-conotoxin GVIAPercentage of neuronsType 2 phenotypeT-type currentType 2 neuronsCalcium current propertiesType 1 neuronsControl cells
1999
The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter
Imaizumi T, Kocsis J, Waxman S. The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter. Brain Research 1999, 817: 84-92. PMID: 9889329, DOI: 10.1016/s0006-8993(98)01214-1.Peer-Reviewed Original ResearchConceptsVoltage-gated Ca2Spinal cord axonsAnoxic injuryDorsal columnsR-type voltage-gated Ca2N-type calcium channelsSpinal cord white matterRat dorsal columnsDorsal column axonsR-type Ca2Rat spinal cordCord white matterT-type channelsInflux of Ca2Dose-dependent mannerLoss of conductionAxonal conductionSpinal cordChannel blockersCalcium channelsSurface stimulationWhite matterPerfusion solutionInjuryGlass microelectrodes