Modulation of neuronal activity in the hippocampus by 5-hydroxytryptamine and 5-hydroxytryptamine1a selective drugs
Peroutka S, Mauk M, Kocsis J. Modulation of neuronal activity in the hippocampus by 5-hydroxytryptamine and 5-hydroxytryptamine1a selective drugs. Neuropharmacology 1987, 26: 139-146. PMID: 2884586, DOI: 10.1016/0028-3908(87)90201-2.Peer-Reviewed Original ResearchConceptsTVX Q 7821Hippocampal slice preparationSlice preparationDose-dependent mannerMicromolar concentrationsApplication of drugsPopulation spikesRadioligand techniquesOH-DPATSchaffer collateralsHippocampal membranesNeuronal activityPyramidal layerKetanserinBaseline levelsBuspironeInitial increaseDPATSelective drugsDrugsField potentialsPhysiological effectsPopulationSimilar affinityBenzisothiazol-3