2000
Excitability changes of dorsal root axons following nerve injury: implications for injury-induced changes in axonal Na+ channels
Nonaka T, Honmou O, Sakai J, Hashi K, Kocsis J. Excitability changes of dorsal root axons following nerve injury: implications for injury-induced changes in axonal Na+ channels. Brain Research 2000, 859: 280-285. PMID: 10719075, DOI: 10.1016/s0006-8993(00)01979-x.Peer-Reviewed Original ResearchConceptsDorsal root axonsNerve injuryDorsal rootsAction potentialsCutaneous afferent axonsSciatic nerve ligationAfferent cell bodiesInjury-induced changesRat dorsal rootSucrose gap chamberTarget disconnectionNerve ligationExcitability changesSpinal cordAfferent axonsTrophic supportRoot ligationRefractory periodCell bodiesElectrophysiological recordingsAxonsInjuryDepolarizationLigationPrevious studies
1980
Absence of potassium conductance in central myelinated axons
Kocsis J, Waxman S. Absence of potassium conductance in central myelinated axons. Nature 1980, 287: 348-349. PMID: 7421994, DOI: 10.1038/287348a0.Peer-Reviewed Original ResearchConceptsCentral myelinated axonsMyelinated axonsAction potentialsPotassium conductanceDorsal column axonsVoltage-clamp experimentsLate outward currentOutward currentsAxonsSodium ion permeabilityLate increaseDepolarization phasePotassium permeabilityAxonal membraneRepolarizationMyelinInitial increaseVoltage-dependent changesSodium inactivationDemyelinationPrevious studies