The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis
Honmou O, Oyelese A, Kocsis J. The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis. Brain Research 1995, 692: 273-277. PMID: 8548315, DOI: 10.1016/0006-8993(95)00634-3.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsFree GABA levelsField potential analysisNipecotic acidGABA levelsPopulation excitatory postsynaptic potentialEffects of microapplicationRelease of GABAGABAA receptor activationAdult rat brainMechanism of actionGABA releasePartial seizuresAnticonvulsant gabapentinPresynaptic volleyPostsynaptic potentialsBath applicationHippocampal slicesRat brainGBP treatmentHippocampal cellsBlock uptakeGabapentinReceptor activationGABAModulation of axonal excitability by neurotransmitter receptors
KOCSIS J, SAKATANI K. Modulation of axonal excitability by neurotransmitter receptors. 1995, 281-295. DOI: 10.1093/acprof:oso/9780195082937.003.0014.Peer-Reviewed Original ResearchNeurotransmitter receptorsGABAA receptorsAxonal GABAA receptorsFunctional GABAA receptorsOptic nerve developmentOptic nerve axonsGABAA receptor activationPossible modulatory roleMammalian nervous systemAxonal excitabilityTrophic influenceNervous systemNerve developmentModulatory roleElectrophysiological propertiesReceptor activationImpulse conductionNerve axonsCertain axonsAxonal regionsReceptorsPossible functional significanceAxonsTransient presenceFunctional significance