1987
Physiological properties of regenerated rat sciatic nerve following lesions at different postnatal ages
Bowe C, Kocsis J, Waxman S, Hildebrand C. Physiological properties of regenerated rat sciatic nerve following lesions at different postnatal ages. Brain Research 1987, 34: 123-131. DOI: 10.1016/0165-3806(87)90201-x.Peer-Reviewed Original ResearchControl nervesPostnatal ageSciatic nerveRegenerated nervesRegenerated rat sciatic nerveFrequency-following abilityOlder postnatal ageSciatic crush lesionRegenerated sciatic nerveAge 3 weeksCompound action potentialDifferent postnatal agesRat sciatic nerveWhole-nerve responseMonths of ageRelative refractory periodCrush lesionPharmacological blockadeNerve responsesSlight prolongationNerveElectrophysiological propertiesAction potentialsRefractory periodOlder age
1986
Action potential characteristics of demyelinated rat sciatic nerve following application of 4-aminopyridine
Targ E, Kocsis J. Action potential characteristics of demyelinated rat sciatic nerve following application of 4-aminopyridine. Brain Research 1986, 363: 1-9. PMID: 3004637, DOI: 10.1016/0006-8993(86)90652-9.Peer-Reviewed Original ResearchConceptsAction potentialsSciatic nerveFrequency-following abilityMultiple spike dischargesSite of demyelinationCompound action potentialPotassium channel blockerRat sciatic nerveAction potential characteristicsVariety of abnormalitiesAbsolute refractory periodExcitability changesPharmacological blockadeSpontaneous firingDemyelinated axonsChannel blockersConduction slowingConduction blockSpike dischargesLesion siteRefractory periodExcitability propertiesClinical useAxonsPotassium channels