2000
Voltage-Gated Calcium Currents in Axotomized Adult Rat Cutaneous Afferent Neurons
Baccei M, Kocsis J. Voltage-Gated Calcium Currents in Axotomized Adult Rat Cutaneous Afferent Neurons. Journal Of Neurophysiology 2000, 83: 2227-2238. PMID: 10758131, DOI: 10.1152/jn.2000.83.4.2227.Peer-Reviewed Original ResearchConceptsVoltage-gated calcium currentsCutaneous afferent neuronsPA/pFNerve injuryCutaneous afferentsType 1 cellsBarium currentsAfferent neuronsHVA currentsCalcium currentLow threshold T-type currentWhole-cell patch-clamp techniqueDorsal root ganglion neuronsCell patch-clamp techniqueFluoro-Gold labelingOmega-agatoxin TKSciatic nerve injuryOmega-conotoxin GVIAPercentage of neuronsType 2 phenotypeT-type currentType 2 neuronsCalcium current propertiesType 1 neuronsControl cells
1999
Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy
Everill B, Kocsis J. Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy. Journal Of Neurophysiology 1999, 82: 700-708. PMID: 10444667, DOI: 10.1152/jn.1999.82.2.700.Peer-Reviewed Original ResearchConceptsDorsal root ganglion neuronsCutaneous afferent neuronsAfferent neuronsGanglion neuronsPotassium currentWhole-cell patch-clamp recordingsCell patch-clamp recordingsPrimary afferent neuronsEffects of axotomyPatch-clamp recordingsControl cellsAppropriate ion replacementAcute ligationNerve ligationDRG neuronsExcitability changesChannel blockersNeuronal excitabilityPharmacological componentsAxotomyNeuronsLigationBasis of sensitivityCellsBlockers