2013
Paracrine Loop of Keratinocyte Proliferation and Directed Neuritic Outgrowth in a Neuroepithelial Coculture
Radtke C, Rennekampff H, Reimers K, Vogt P, Kocsis J. Paracrine Loop of Keratinocyte Proliferation and Directed Neuritic Outgrowth in a Neuroepithelial Coculture. Annals Of Plastic Surgery 2013, Publish Ahead of Print: &na;. DOI: 10.1097/sap.0b013e318276d946.Peer-Reviewed Original ResearchNerve growth factorNeuritic outgrowthDRG neuronsHuman keratinocytesNeurotrophin nerve growth factorDorsal root ganglion neuronsCutaneous afferent axonsKeratinocyte proliferationAnti-NGF antibodyWound healingChronic nonhealing woundsProliferation of keratinocytesNGF levelsSkin innervationPrimary human keratinocytesNeurotrophic factorGanglion neuronsAfferent axonsParacrine loopNonhealing woundsMitogenic effectCell bodiesNeuritic processesGrowth factorNeurons
2000
Excitability changes of dorsal root axons following nerve injury: implications for injury-induced changes in axonal Na+ channels
Nonaka T, Honmou O, Sakai J, Hashi K, Kocsis J. Excitability changes of dorsal root axons following nerve injury: implications for injury-induced changes in axonal Na+ channels. Brain Research 2000, 859: 280-285. PMID: 10719075, DOI: 10.1016/s0006-8993(00)01979-x.Peer-Reviewed Original ResearchConceptsDorsal root axonsNerve injuryDorsal rootsAction potentialsCutaneous afferent axonsSciatic nerve ligationAfferent cell bodiesInjury-induced changesRat dorsal rootSucrose gap chamberTarget disconnectionNerve ligationExcitability changesSpinal cordAfferent axonsTrophic supportRoot ligationRefractory periodCell bodiesElectrophysiological recordingsAxonsInjuryDepolarizationLigationPrevious studies
1998
The delayed depolarization in rat cutaneous afferent axons is reduced following nerve transection and ligation, but not crush: Implications for injury‐induced axonal NA + channel reorganization
Sakai J, Honmou O, Kocsis J, Hashi K. The delayed depolarization in rat cutaneous afferent axons is reduced following nerve transection and ligation, but not crush: Implications for injury‐induced axonal NA + channel reorganization. Muscle & Nerve 1998, 21: 1040-1047. PMID: 9655122, DOI: 10.1002/(sici)1097-4598(199808)21:8<1040::aid-mus8>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsCutaneous afferent axonsNerve injurySural nerveNerve transectionAfferent axonsAction potentialsCell bodiesCutaneous afferent neuronsPeripheral nerve injuryAfferent cell bodiesSucrose gap chamberRat sural nerveTarget disconnectionAfferent neuronsPeripheral targetsAxonal NaNerveRefractory periodAxonsTransectionCompound actionDepolarizationSimilar changesInjuryTarget connections
1997
Functional Repair of Myelinated Fibers in the Spinal Cord by Transplantation of Glial Cells
Waxman S, Kocsis J. Functional Repair of Myelinated Fibers in the Spinal Cord by Transplantation of Glial Cells. Altschul Symposia Series 1997, 283-298. DOI: 10.1007/978-1-4615-5949-8_28.Peer-Reviewed Original ResearchConduction velocityMyelinated axonsMyelin sheathNon-myelinated fibresClinical deficitsMyelin damageConduction abnormalitiesDemyelinated axonsSpinal cordGlial cellsMyelinated fibersConduction blockSynaptic terminalsAction potentialsRefractory periodCell bodiesDemyelinated fibersAxonsFunctional repair
1995
Action in the Dendrites: A Revisitation of Dendritic Action Potentials
Kocsis J. Action in the Dendrites: A Revisitation of Dendritic Action Potentials. The Neuroscientist 1995, 1: 312-316. DOI: 10.1177/107385849500100602.Peer-Reviewed Original ResearchDendritic action potentialsSynaptic inputsAction potentialsCell bodiesPassive electrotonic spreadSimultaneous patch-clamp recordingsInitial axon segmentPatch-clamp recordingsRat hippocampal neuronsDendritic electrogenesisHippocampal neuronsDendritic spinesClamp recordingsElectrophysiological studiesPrimary siteAxon segmentsNeuronsNerve impulsesMembrane potential changesElectrotonic spreadUp-DateDendritesExcitatorySynapticSpine
1993
Transient presence of GABA in astrocytes of the developing optic nerve
Ochi S, Lim J, Rand M, During M, Sakatani K, Kocsis J. Transient presence of GABA in astrocytes of the developing optic nerve. Glia 1993, 9: 188-198. PMID: 8294149, DOI: 10.1002/glia.440090304.Peer-Reviewed Original ResearchConceptsWhole optic nerveOptic nerveHigh-pressure liquid chromatographyGABA immunoreactivityPostnatal developmentEnzyme glutamic acid decarboxylaseIntact optic nerveRat optic nerveNeonatal optic nerveGlutamic acid decarboxylaseAstrocyte cell bodiesPostnatal day 20GABA immunostainingGFAP stainingPostnatal weekGABA stainingNerveCultured astrocytesAstrocytesDay 20GABAAcid decarboxylaseCell bodiesDevelopmental time courseImmunoreactivity
1990
Dendritic action potentials activated by NMDA receptor-mediated EPSPs in CA1 hippocampal pyramidal cells
Poolos N, Kocsis J. Dendritic action potentials activated by NMDA receptor-mediated EPSPs in CA1 hippocampal pyramidal cells. Brain Research 1990, 524: 342-346. PMID: 1981329, DOI: 10.1016/0006-8993(90)90714-m.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsCA1 hippocampal pyramidal cellsDendritic action potentialsHippocampal pyramidal cellsPyramidal cellsRat CA1 hippocampal pyramidal cellsNMDA receptor-mediated excitatory postsynaptic potentialsAction potentialsDendritic excitatory postsynaptic potentialsN-methyl-D-aspartate receptorsPyramidal cell bodiesShort-term potentiationIntradendritic recordingsPostsynaptic potentialsSynaptic responsesDendritic arborsDendritic conductancesRepetitive stimulationDendritic spikesSomatic recordingsCell bodiesSubthreshold responsesMultiple sitesCellsRecordings