1998
Decreased brain glucose utilization in patients with Cushing's disease.
Brunetti A, Fulham M, Aloj L, De Souza B, Nieman L, Oldfield E, Di Chiro G. Decreased brain glucose utilization in patients with Cushing's disease. Journal Of Nuclear Medicine 1998, 39: 786-90. PMID: 9591575.Peer-Reviewed Original ResearchConceptsCushing's diseaseCerebral glucose metabolismGlucose metabolismPET scansDecreased brain glucose utilizationIncreased plasma glucocorticoid levelsRadiotracer 18F-fluorodeoxyglucoseFDG-PET scansGlucocorticoid levelsAge-matched normal control subjectsFDG-PET studiesNormal control subjectsPlasma glucocorticoid levelsIncreased glucose metabolismIncreased glucocorticoid levelsMeasurements of cerebral glucose metabolismPostsurgery valuesDecreased cerebral glucose metabolismPituitary adenomasAbnormal cerebral glucose metabolismSurgical removalBrain glucose utilizationControl subjectsCentral actionCushing
1990
Pituitary microadenomas: a PET study.
De Souza B, Brunetti A, Fulham M, Brooks R, DeMichele D, Cook P, Nieman L, Doppman J, Oldfield E, Di Chiro G. Pituitary microadenomas: a PET study. Radiology 1990, 177: 39-44. PMID: 2399336, DOI: 10.1148/radiology.177.1.2399336.Peer-Reviewed Original ResearchConceptsSimultaneous bilateral inferior petrosal sinus samplingPositron emission tomographyFluorine-18-2-fluorodeoxyglucoseComputed tomographyMR imagingBilateral inferior petrosal sinus samplingInferior petrosal sinus samplingCases of Cushing's diseasePositron emission tomography resultsPetrosal sinus samplingMaterial-enhanced CTMagnetic resonance (MR) imagingStudy of healthy subjectsHealthy control subjectsPositron emission tomography studiesPituitary microadenomaCushing's diseaseSinus samplingControl subjectsPET readingsHealthy subjectsPositive readingsEmission tomographyFluorine-18Image reading