2024
Outcome-based Risk Assessment of Non-HLA Antibodies in Heart Transplantation: A Systematic Review
Panicker A, Prokop L, Hacke K, Jaramillo A, Griffiths L. Outcome-based Risk Assessment of Non-HLA Antibodies in Heart Transplantation: A Systematic Review. The Journal Of Heart And Lung Transplantation 2024, 43: 1450-1467. PMID: 38796046, DOI: 10.1016/j.healun.2024.05.012.Peer-Reviewed Original ResearchConceptsNon-HLA antibodiesEndomyocardial biopsyHeart transplantationRejection pathologyDonor-specific anti-human leukocyte antigen antibodiesAnti-human leukocyte antigen antibodiesHistocompatibility complex class I chain-related gene ANon-human leukocyte antigenSystematic reviewNon-HLA antigensStrength of evidenceAntibody-mediated rejectionInvasive endomyocardial biopsyPositive endomyocardial biopsyClinical risk stratificationHLA-DSAHT recipientsRejection monitoringLeukocyte antigenRisk stratificationRejection eventsRisk factorsInclusion criteriaAntigen antibodiesAntibodies
2021
Shotgun Immunoproteomics for Identification of Nonhuman Leukocyte Antigens Associated With Cellular Dysfunction in Heart Transplant Rejection
Gates K, Panicker A, Biendarra-Tiegs S, Vetr N, Higuita M, Nelson T, Pereira N, Griffiths L. Shotgun Immunoproteomics for Identification of Nonhuman Leukocyte Antigens Associated With Cellular Dysfunction in Heart Transplant Rejection. Transplantation 2021, 106: 1376-1389. PMID: 34923540, DOI: 10.1097/tp.0000000000004012.Peer-Reviewed Original ResearchMeSH KeywordsGraft RejectionHeart TransplantationHLA AntigensHumansImmunoglobulin GProteomicsTissue DonorsConceptsAntibody-mediated rejectionHeart transplant recipientsAntigen-specific responsesNon-HLAPrevalence antigensAcute rejectionTransplant recipientsAbsence of donor-specific anti-HLA antibodiesDonor-specific anti-HLA antibodiesNon-HLA antibody responsesAntibody-mediated rejection patientsNon-AMR patientsAnti-HLA antibodiesHeart transplant rejectionPatient immunoglobulin GHigh-prevalence antigenEndothelial cell functionEndomyocardial biopsyAllograft rejectionGraft rejectionHeart biopsiesTransplant rejectionAntibody responseImmunofluorescence stainingPatients