2023
Complete tolerogenic response adjuvant stimulates Treg response to immunization
JANJAM S, Geng Y, yan Z, Shin S, Joshi K, Panicker A, shankar A, Elangovan R, Koehler J, Gnanasekar V, williams A, Feng A, ellis C, Vattikota A, Chen A, Zheng G. Complete tolerogenic response adjuvant stimulates Treg response to immunization. The Journal Of Immunology 2023, 210: 158.08-158.08. DOI: 10.4049/jimmunol.210.supp.158.08.Peer-Reviewed Original ResearchTolerogenic adjuvantAntigen-specific immunosuppressionMonophosphoryl lipid AMouse model of atherosclerosisResponse to immunizationTreg responsesTreg cellsModel of atherosclerosisAutoimmune/inflammatory diseasesVaccination regimenMurine modelNovel adjuvantsAntigen immunizationApoE-/- mouse modelVaccine adjuvantsB antigenAdjuvantImmunogenic substancesTregsVaccineImmunological illnessesImmunityLipid AComplete Tolerogenic Adjuvant Stimulates Regulatory T Cell Response to Immunization.
Zheng G, Geng Y, Yan Z, Shin S, Joshi K, Panicker A, Shankar A, Elangovan R, Koehler J, Gnanasekar V, Gilles J, Munirathinam G, Chen A. Complete Tolerogenic Adjuvant Stimulates Regulatory T Cell Response to Immunization. The Journal Of Immunology 2023, 210: 609-617. PMID: 36602931, PMCID: PMC9998350, DOI: 10.4049/jimmunol.2200463.Peer-Reviewed Original Research
2019
Raising Endogenous Anti-HMGB1 IgM Antibody for Athero-Protection in the Apoe−/− Mouse Model of Atherosclerosis
Hariharasubramanian A, Elangovan R, Shankar A, Giacobazzi M, Broski A, Panicker A, Shin S, Chen A, Zheng G. Raising Endogenous Anti-HMGB1 IgM Antibody for Athero-Protection in the Apoe−/− Mouse Model of Atherosclerosis. The Journal Of Immunology 2019, 202: 196.30-196.30. DOI: 10.4049/jimmunol.202.supp.196.30.Peer-Reviewed Original ResearchMouse model of atherosclerosisWestern type dietModel of atherosclerosisB cellsIgM antibodiesReduce atherosclerosisIgM-producing B cellsB-1 cellsAnti-atherogenic efficacyNon-treated groupAortic archTreated miceAortic rootC57BL/6 miceApoE-/- mouse modelMouse modelIgM responseWeeks of ageHealthy humansAthero-protectiveMiceAtherosclerosisImmunitySpontaneous productionType diet