2021
Shotgun Immunoproteomics for Identification of Nonhuman Leukocyte Antigens Associated With Cellular Dysfunction in Heart Transplant Rejection
Gates K, Panicker A, Biendarra-Tiegs S, Vetr N, Higuita M, Nelson T, Pereira N, Griffiths L. Shotgun Immunoproteomics for Identification of Nonhuman Leukocyte Antigens Associated With Cellular Dysfunction in Heart Transplant Rejection. Transplantation 2021, 106: 1376-1389. PMID: 34923540, DOI: 10.1097/tp.0000000000004012.Peer-Reviewed Original ResearchConceptsAntibody-mediated rejectionHeart transplant recipientsAntigen-specific responsesNon-HLAPrevalence antigensAcute rejectionTransplant recipientsAbsence of donor-specific anti-HLA antibodiesDonor-specific anti-HLA antibodiesNon-HLA antibody responsesAntibody-mediated rejection patientsNon-AMR patientsAnti-HLA antibodiesHeart transplant rejectionPatient immunoglobulin GHigh-prevalence antigenEndothelial cell functionEndomyocardial biopsyAllograft rejectionGraft rejectionHeart biopsiesTransplant rejectionAntibody responseImmunofluorescence stainingPatients
2020
Role of non-HLA antigens in cardiac transplant rejection
Panicker A, Gates K, Biendarra-Tiegs S, Vetr N, Higuita M, Nelson T, Pereira N, Griffiths L. Role of non-HLA antigens in cardiac transplant rejection. The Journal Of Immunology 2020, 204: 161.7-161.7. DOI: 10.4049/jimmunol.204.supp.161.7.Peer-Reviewed Original ResearchNon-HLA antigensNon-HLA antibodiesHeart transplant patientsHuman leukocyte antigenImmune responseTransplant patientsTransplant rejectionDonor-specific anti-HLA antibodiesTerm survivalNon-HLA antibody responsesSpecific anti-HLA antibodiesAnti-HLA antibodiesCardiac allograft vasculopathyHeart transplant recipientsCardiac transplant rejectionHeart transplant rejectionCell mediated rejectionAdaptive immune responsesLong-term survivalShort-term survivalAllograft vasculopathyRejection incidenceAcute rejectionTransplant recipientsAntigen expression