Tingting Wang
Associate Research ScientistAbout
Research
Publications
2026
Carabrone alleviates neuroinflammation by covalently targeting ubiquitin conjugating enzyme UBE2D3 in experimental autoimmune encephalomyelitis
Tang H, Sun L, Jia B, Xu T, Xiao J, Zhang R, Wang T, Ji S, Xu Y. Carabrone alleviates neuroinflammation by covalently targeting ubiquitin conjugating enzyme UBE2D3 in experimental autoimmune encephalomyelitis. European Journal Of Pharmacology 2026, 1033: 179213. PMID: 42628619, DOI: 10.1016/j.ejphar.2026.179213.Peer-Reviewed Original ResearchCol4a1 mutation in a mouse model of cerebral small vessel disease causes white matter defects that can be modulated by targeting protein folding
Brezzo G, Pokhilko A, Moss J, Koudelka J, Jansen M, Lennen R, Thompson G, Fialova N, Konstantinidou S, Yau J, Boland E, Williams A, Allan S, Granata A, Sinha S, Wang T, Markus H, Fischer R, Cader M, Van Agtmael T, Horsburgh K. Col4a1 mutation in a mouse model of cerebral small vessel disease causes white matter defects that can be modulated by targeting protein folding. Matrix Biology 2026, 149: 102044. PMID: 42607872, DOI: 10.1016/j.matbio.2026.102044.Peer-Reviewed Original ResearchCSF-1 promotes microglial proliferation and ameliorates ischemic brain injury
Deng S, Li Q, Liu P, Cao X, Zhang S, Xia S, Bao X, Wang T, Li H, Xu Y. CSF-1 promotes microglial proliferation and ameliorates ischemic brain injury. Neurochemistry International 2026, 199: 106233. PMID: 42542249, DOI: 10.1016/j.neuint.2026.106233.Peer-Reviewed Original ResearchGut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease
Qiao S, Fan S, Xu J, Xu Z, Peng C, Qu J, Bing Z, Zhou S, Shen S, Xu G, Zhao Y, Wang T. Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease. Advanced Science 2026, 13: e14830. PMID: 42052722, PMCID: PMC13334940, DOI: 10.1002/advs.202514830.Peer-Reviewed Original ResearchNext-generation in vivo CAR-T expansion strategies: Unlocking durable anti-tumor responses in solid tumors
Sun Z, Wei L, Pan X, Yan W, Wang T, Wang X. Next-generation in vivo CAR-T expansion strategies: Unlocking durable anti-tumor responses in solid tumors. Critical Reviews In Oncology/Hematology 2026, 223: 105342. PMID: 42013999, DOI: 10.1016/j.critrevonc.2026.105342.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIntraovarian injection of securinine stimulates the growth of small ovarian follicles by reducing stromal suppression
Zhao Y, Liu D, Lin Z, Deng S, Zhao X, Sun Y, Zhang Y, Zhang Q, Gu J, Xiao Y, Wang T, Lu H, Zhao J, Chan K, Li Y, Yeung W, Liu K. Intraovarian injection of securinine stimulates the growth of small ovarian follicles by reducing stromal suppression. Nature Communications 2026, 17: 5061. PMID: 41974717, PMCID: PMC13243526, DOI: 10.1038/s41467-026-71691-7.Peer-Reviewed Original ResearchSelective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor
Zhao X, Yu C, Adamson A, Zhao A, Zhou H, Sharma P, Wang T. Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor. Science Advances 2026, 12: eaeb1134. PMID: 41931622, PMCID: PMC13048245, DOI: 10.1126/sciadv.aeb1134.Peer-Reviewed Original ResearchPhomones A−C, Anti‐Vibrio α‐Pyrones From Phoma sp. NBUF235 Associated With an Ircinia Sponge From the Marine Mesophotic Zone
Lai T, Li J, Wei T, Zheng Q, Shu K, Khan S, Zhang R, He S, Wang T. Phomones A−C, Anti‐Vibrio α‐Pyrones From Phoma sp. NBUF235 Associated With an Ircinia Sponge From the Marine Mesophotic Zone. Chemistry & Biodiversity 2026, 23: e02573. PMID: 41893952, DOI: 10.1002/cbdv.202502573.Peer-Reviewed Original ResearchDiscovery of novel ten-membered lactones as osteoblastogenesis agents targeting Wnt/β-catenin signaling pathway
Zhai Y, Zhang J, Yang J, Wang T, Gao J, Wang W, Han W. Discovery of novel ten-membered lactones as osteoblastogenesis agents targeting Wnt/β-catenin signaling pathway. Bioorganic Chemistry 2026, 175: 109768. PMID: 41865565, DOI: 10.1016/j.bioorg.2026.109768.Peer-Reviewed Original ResearchFrom structural evolution to an AI-driven future of 5-HT1F receptor agonists for migraine therapy
Lin L, Wu J, Wang T, Cao Y, Zhang D, Jin H, He S. From structural evolution to an AI-driven future of 5-HT1F receptor agonists for migraine therapy. European Journal Of Medicinal Chemistry 2026, 309: 118768. PMID: 41864040, DOI: 10.1016/j.ejmech.2026.118768.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements