Ya-Chi Ho, MD, PhD

Assistant Professor of Microbial Pathogenesis and Medicine (Infectious Diseases); Investigator, HIV Reservoirs and Viral Eradication Transformative Science Group (Cure TSG)

Departments & Organizations

Microbial Pathogenesis: Ya-Chi Ho Lab

Internal Medicine

Virology Laboratories

Yale Cancer Center: Virus and Other Infection-associated Cancers

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology | Microbiology

Biography

Dr. Ho takes a molecular virology approach to examine HIV persistence and develop HIV cure strategies. Using clinical samples from HIV-infected individuals, the Ho lab investigates host-HIV interactions with particular interests in HIV-1-host RNA landscape (using single-cell RNAseq), CD4 T cell expansion dynamics, HIV-host genome interactions, and HIV-1-specific silencing, and immune escape mechanisms. Dr. Ho was an infectious disease attending physician in Taiwan. She received her PhD (2013) and postdoctoral training at Johns Hopkins University School of Medicine in Dr. Robert F. Siliciano's lab. She was a tenure track instructor (2016) and then an assistant professor (2017) at Johns Hopkins School of Medicine before she joined Yale School of Medicine in September 2017. As a investigator of the AIDS Clinical Trial Group (ACTG) and the BEAT HIV Martin Delaney Collaboratory, she actively collaborate with geneticists, bioinformaticians, immunologists and physicians to study HIV-1 persistence. She is currently funded by an NIH R01 grant and an NIH R61/R33 grant (August 2018) as the Principal Investigator.

Education & Training

PhD Johns Hopkins University School of Medicine, Cellular and Molecular Medicine (2013)
MMS National Taiwan University, Clinical Medicine (2007)
MD National Cheng Kung University, Medicine (2002)
Postdoctoral fellow Johns Hopkins School of Medicine
Clinical fellow National Taiwan University Hospital
Resident National Taiwan University Hospital
Clinical clerkship Duke University Medical Center
Clinical clerkship Yale University

Honors & Recognition

  • Andy Kaplan PrizeCold Spring Harbor Laboratory Meetings on Retroviruses (2018)

  • Gilead Sciences Research Scholar in HIVGilead Sciences (2018)

  • Rudolf J. Anderson FellowshipYale University (2018)

  • Lois E. and Franklin H. Top, Jr. Yale ScholarYale University School of Medicine (2017)

  • Distinguished Alumni AwardNational Cheng Kung University (2016)

  • W. W. Smith Charitable Foundation AIDS Research AwardW. W. Smith Charitable Foundation (2016)

  • Phi Beta KappaPhi Beta Kappa Honorary Society (2014)

  • Michael Shanoff Johns Hopkins Young Investigator AwardJohns Hopkins University School of Medicine (2014)

  • Young Investigator AwardCROI (2013)

  • Howard Hughes International Student Research FellowshipHoward Hughes Medical Institute (2011)

  • Best Teaching Resident AwardNational Taiwan University Hospital (2007)

  • Scholarship for PhD Studies AbroadMinistry of Education, Taiwan (2007)

  • Best Resident AwardDepartment of Medicine, National Taiwan University Hospital (2003, 2004)

  • Phi Tau PhiPhi Tau Phi Honorary Society, Taiwan (2002)

Professional Service

  • AIDS 2018, The International AIDS Society Meeting (2018) Co-Chair, "Poking, prodding and purging the final reservoir frontier" session

  • NIH, AIDS Immunology and Pathogenesis Study Section (2018) Reviewer

  • Ad hoc reviewer, Immunity, Science Translational Medicine, JCI, PNAS, Cell Reports, Scientific Report, mBio, PLoS Pathogens, Retrovirology, Journal of Infectious Diseases (2018 - Present) Reviewer

  • Cold Spring Harbor Meetings on Retroviruses (2018) Panelist and moderator, "HIV reservoirs and latency – What are they and how can we tackle them?"

  • Millennium Science Initiative (2018) Study section

  • Czech Science Foundation (2017) Study section

  • Johns Hopkins University School of Medicine (2017) Assistant Professor of Medicine

  • NIH Special Emphasis Panel Study Section (2016 - 2017) Ad hoc reviewer

  • American Society for Microbiology Annual Meeting (2016) Co-convener, New Frontiers in HIV Cure session, American Society for Microbiology Annual Meeting (ASM Microbe), Boston, 2016

  • DC CFAR Faculty Developmental Grant Study Section (2016) Ad hoc reviewer

  • Johns Hopkins University School of Medicine (2015 - 2017) Instructor in Medicine

  • Guest Editor, Journal of Virus Eradication (2015) Guest Editor, Journal of Virus Eradication

  • Johns Hopkins University School of Medicine (2014 - 2015) Research Associate

  • American Society for Microbiology (2011 - 2017) Member

Activities

  • Invited Speaker and session co-chair, AIDS 2018, The International AIDS Meeting Amsterdam, Netherlands (2018)

  • Invited Speaker, AACR Special Conference on Cancer: Dormancy and Residual Disease Montreal, Canada (2018 - 2018)

  • Invited Speaker, University of Washington/Fred Hutchinson Center for AIDS Research Seminar Seattle, United States (2018 - 2018)

  • Invited Speaker, Keystone Symposia, HIV and Co-Infections Whistler, Canada (2018 - 2018)

  • Invited Speaker, The International Meeting of the Institute of Human Virology Baltimore, United States (2017 - 2017)

  • Invited Speaker, Conference on Cell & Gene Therapy for HIV Cure Seattle, United States (2017 - 2017)

  • Invited Speaker, The Department of Microbiology, Immunology, and Tropical Medicine Seminar Washington, United States (2015 - 2015)

Edit this profile

Contact Info

Ya-Chi Ho, MD, PhD
Lab Location
Ya-Chi Ho LabBoyer Center for Molecular Medicine
295 Congress Avenue, Rm BCMM 349

New Haven, CT 06510
View on map...
Office Location
Boyer Center for Molecular Medicine
295 Congress Avenue, Rm BCMM 354E

New Haven, CT 06510
View on map...

Curriculum Vitae

Ya-Chi Ho Lab