2017
Ode to Glia: A Tribute to Bruce Ransom
Waxman SG, Black JA. Ode to Glia: A Tribute to Bruce Ransom. Neurochemical Research 2017, 42: 2442-2442. PMID: 28921457, DOI: 10.1007/s11064-017-2368-8.Peer-Reviewed Original Research
1997
Axon-glia interactions: Building a smart nerve fiber
Waxman S. Axon-glia interactions: Building a smart nerve fiber. Current Biology 1997, 7: r406-r410. PMID: 9210363, DOI: 10.1016/s0960-9822(06)00203-x.Peer-Reviewed Original Research
1996
Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides
Roy M, Saal D, Perney T, Sontheimer H, Waxman S, Kaczmarek L. Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides. Glia 1996, 18: 177-184. PMID: 8915650, DOI: 10.1002/(sici)1098-1136(199611)18:3<177::aid-glia2>3.0.co;2-x.Peer-Reviewed Original ResearchConceptsGlial cellsKv1.5 channel proteinSpinal cordKv1.5 proteinCultured spinal cordTEA-insensitive currentSpinal cord astrocytesRectifier current densityPotassium channel typesAntisense oligodeoxynucleotide treatmentKv1.5 potassium channelAdult ratsCerebellar slicesChannel proteinsAstrocytesOligodeoxynucleotide treatmentPotassium channelsRectifier currentEndfoot processesSuch treatmentCurrent activationAntisense oligodeoxynucleotidesCordCellsTreatmentVoltage-gated Na+ channels in glia: properties and possible functions
Sontheimer H, Black J, Waxman S. Voltage-gated Na+ channels in glia: properties and possible functions. Trends In Neurosciences 1996, 19: 325-331. PMID: 8843601, DOI: 10.1016/0166-2236(96)10039-4.Peer-Reviewed Original Research
1987
Chapter 11 Rules governing membrane reorganization and axon—glial interactions during the development of myelinated fibers
Waxman S. Chapter 11 Rules governing membrane reorganization and axon—glial interactions during the development of myelinated fibers. Progress In Brain Research 1987, 71: 121-141. PMID: 3588937, DOI: 10.1016/s0079-6123(08)61819-1.Peer-Reviewed Original Research
1986
Effects of delayed myelination by oligodendrocytes and Schwann cells on the macromolecular structure of axonal membrane in rat spinal cord
Black J, Waxman S, Sims T, Gilmore S. Effects of delayed myelination by oligodendrocytes and Schwann cells on the macromolecular structure of axonal membrane in rat spinal cord. Brain Cell Biology 1986, 15: 745-761. PMID: 3819778, DOI: 10.1007/bf01625192.Peer-Reviewed Original ResearchConceptsDorsal funiculusSpinal cordSchwann cellsMyelin sheathAxonal membraneControl spinal cordsLumbosacral spinal cordSchwann cell ensheathmentRat spinal cordThin myelin sheathsDorsal spinal rootsDays of ageVoltage-sensitive sodium channelsSubsequent myelinationSpinal rootsMyelinated fibersLarge axonsCordMyelinationOligodendrocytesFuniculusSodium channelsIMP densityE-face intramembranous particlesInternodal axolemmaA quantitative study of developing axons and glia following altered gliogenesis in rat optic nerve
Black J, Waxman S, Ransom B, Feliciano M. A quantitative study of developing axons and glia following altered gliogenesis in rat optic nerve. Brain Research 1986, 380: 122-135. PMID: 2428420, DOI: 10.1016/0006-8993(86)91436-8.Peer-Reviewed Original ResearchConceptsRat optic nerveOptic nerve volumeNormal optic nervesOptic nerveNerve volumeTotal glial cellsNerve cross sectionsGlial cellsMyelinated fibersAxonal diameterAge-matched control tissueNeonatal rat optic nerveOptic nerve cross sectionsConcomitant marked reductionProgenitor cellsNumber of oligodendrogliaAge-matched controlsGlial cell developmentDays of ageEnsheathed axonsSystemic injectionNerveAstrocytic lineageControl tissuesGliaMolecular structure of the axolemma of developing axons following altered gliogenesis in rat optic nerve
Black J, Waxman S. Molecular structure of the axolemma of developing axons following altered gliogenesis in rat optic nerve. Developmental Biology 1986, 115: 301-312. PMID: 2423398, DOI: 10.1016/0012-1606(86)90251-4.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsAzacitidineFreeze FracturingMicroscopy, ElectronMyelin SheathNeurogliaOptic NerveRatsConceptsRat optic nerveOptic nerveMyelinated fibersLarge caliber fibersAxonal diameterNeonatal rat optic nerveP-face IMP densityControl optic nervesDays of ageNodes of RanvierUnensheathed axonsGlial ensheathmentSystemic injectionNerveAxonsGliogenesisIMP densityAxolemmaE-face particlesCell associationIntramembranous particlesRatsOligodendrocytesMyelinEnsheathment
1985
Neurogenesis in Adult Vertebrate Spinal Cord in Situ and in Vitro: A New Model Systema
ANDERSON M, WAXMAN S. Neurogenesis in Adult Vertebrate Spinal Cord in Situ and in Vitro: A New Model Systema. Annals Of The New York Academy Of Sciences 1985, 457: 213-233. PMID: 3913365, DOI: 10.1111/j.1749-6632.1985.tb20807.x.Peer-Reviewed Original ResearchConceptsSpinal cordEpendymal cellsNeuron-specific monoclonal antibodiesSpinal cord tissueSternarchus albifronsStudy of neurogenesisFunctional recoveryNew neuronsCord tissuePositive stainingRecent studiesCultured neuronsCordInjuryNeurogenesisMonoclonal antibodiesNeuronal differentiationNormal morphologic structureCNSExplant culturesNeuronsVertebrate spinal cordSternarchusNew spinal cordNeuronal identityAxo-glial relations in the retina-optic nerve junction of the adult rat: freeze-fracture observations on axon membrane structure
Black J, Waxman S, Hildebrand C. Axo-glial relations in the retina-optic nerve junction of the adult rat: freeze-fracture observations on axon membrane structure. Brain Cell Biology 1985, 14: 887-907. PMID: 3831245, DOI: 10.1007/bf01224803.Peer-Reviewed Original ResearchAxo-glial relations in the retina-optic nerve junction of the adult rat: electron-microscopic observations
Hildebrand C, Remahl S, Waxman S. Axo-glial relations in the retina-optic nerve junction of the adult rat: electron-microscopic observations. Brain Cell Biology 1985, 14: 597-617. PMID: 4067610, DOI: 10.1007/bf01200800.Peer-Reviewed Original ResearchConceptsNerve junctionAdult ratsAstrocytic processesDeficient blood-brain barrierEctopic Schwann cellsFibrous astrocytic processesBlood-brain barrierAxo-glial contactsMyelination of axonsNumerous pinocytotic vesiclesTypical oligodendrocytesGlial ensheathmentGlial cellsUnmyelinated segmentsGlia limitansSchwann cellsUnmyelinated axonsWide perivascular spacesPia materPerivascular spacesOligodendroglial cellsDeficient proliferationUnmyelinated partMyelin sheathSame axonOrganization of Ion Channels in the Myelinated Nerve Fiber
Waxman S, Ritchie J. Organization of Ion Channels in the Myelinated Nerve Fiber. Science 1985, 228: 1502-1507. PMID: 2409596, DOI: 10.1126/science.2409596.Peer-Reviewed Original ResearchRat optic nerve: Disruption of gliogenesis with 5-azacytidine during early postnatal development
Ransom B, Yamate C, Black J, Waxman S. Rat optic nerve: Disruption of gliogenesis with 5-azacytidine during early postnatal development. Brain Research 1985, 337: 41-49. PMID: 2408709, DOI: 10.1016/0006-8993(85)91607-5.Peer-Reviewed Original ResearchConceptsOptic nerveGlial cellsOptic nerve axonsRat optic nerveCompound action potentialEarly postnatal developmentDays of ageOlder nervesNeonatal treatmentBrain extracellular spaceNeuroglial interactionsElectrophysiological studiesNervePostnatal developmentAction potentialsNerve axonsExcitability propertiesMarked reductionMyelin formationGliogenesisMitotic inhibitorsIonic homeostasisExtracellular spaceAgeAnimalsGlial proliferation in the irradiated rat spinal cord
Sims T, Waxman S, Gilmore S. Glial proliferation in the irradiated rat spinal cord. Acta Neuropathologica 1985, 68: 169-172. PMID: 4072625, DOI: 10.1007/bf00688641.Peer-Reviewed Original ResearchConceptsSpinal cordRat spinal cordPost-irradiation intervalsGlial proliferationIncorporation of3H-thymidineGlial cellsAdjacent thin sectionsWhite matterThick plastic sectionsCell bodiesMyelin sheathVentral halfCordOf3H-thymidineAstrogliaIrregular outlinePresent studyMitotic cellsCellsPlastic sectionsBundles of filamentsRatsMyelinationOligodendrocytesMembrane ultrastructure of developing axons in glial cell deficient rat spinal cord
Black J, Sims T, Waxman S, Gilmore S. Membrane ultrastructure of developing axons in glial cell deficient rat spinal cord. Brain Cell Biology 1985, 14: 79-104. PMID: 4009213, DOI: 10.1007/bf01150264.Peer-Reviewed Original Research
1984
Freeze-fracture ultrastructure of the perinodal astrocyte and associated glial junctions
Waxman S, Black J. Freeze-fracture ultrastructure of the perinodal astrocyte and associated glial junctions. Brain Research 1984, 308: 77-87. PMID: 6434150, DOI: 10.1016/0006-8993(84)90919-3.Peer-Reviewed Original ResearchMembrane specialization and axo-glial association in the rat retinal nerve fibre layer: freeze-fracture observations
Black J, Waxman S, Hildebrand C. Membrane specialization and axo-glial association in the rat retinal nerve fibre layer: freeze-fracture observations. Brain Cell Biology 1984, 13: 417-430. PMID: 6481406, DOI: 10.1007/bf01148332.Peer-Reviewed Original ResearchPostnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations
Hildebrand C, Waxman S. Postnatal differentiation of rat optic nerve fibers: Electron microscopic observations on the development of nodes of Ranvier and axoglial relations. The Journal Of Comparative Neurology 1984, 224: 25-37. PMID: 6715578, DOI: 10.1002/cne.902240103.Peer-Reviewed Original ResearchConceptsRat optic nerve fibersOptic nerve fibersNerve fibersUnmyelinated optic nerve axonsPostnatal differentiationOptic nerve axonsPerinodal astrocytic processesAxoglial signallingNodes of RanvierVesiculotubular profilesOptic nerveRat pupsCompact myelin sheathAxolemmal undercoatingAstrocytic processesNerve axonsAxonal diameterMyelin sheathAxon segmentsAxonsAxolemmaRanvierDaysElectron microscopic observationsFunctional differentiationSpecificity in central myelination: evidence for local regulation of myelin thickness
Waxman S, Sims T. Specificity in central myelination: evidence for local regulation of myelin thickness. Brain Research 1984, 292: 179-185. PMID: 6697207, DOI: 10.1016/0006-8993(84)90905-3.Peer-Reviewed Original Research
1983
Ontogenesis of the Axolemma and Axoglial Relationships in Myelinated Fibers: Electrophysiological and Freeze-Fracture Correlates of Membrane Plasticity
Waxman S, Black J, Foster R. Ontogenesis of the Axolemma and Axoglial Relationships in Myelinated Fibers: Electrophysiological and Freeze-Fracture Correlates of Membrane Plasticity. International Review Of Neurobiology 1983, 24: 433-484. PMID: 6360938, DOI: 10.1016/s0074-7742(08)60226-3.Peer-Reviewed Original Research