2014
Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy
Oliva MK, McGarr TC, Beyer BJ, Gazina E, Kaplan DI, Cordeiro L, Thomas E, Dib-Hajj SD, Waxman SG, Frankel WN, Petrou S. Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy. Neurobiology Of Disease 2014, 67: 180-190. PMID: 24657915, PMCID: PMC4298829, DOI: 10.1016/j.nbd.2014.03.007.Peer-Reviewed Original Research
1992
Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger
Stys P, Waxman S, Ransom B. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. Journal Of Neuroscience 1992, 12: 430-439. PMID: 1311030, PMCID: PMC6575619, DOI: 10.1523/jneurosci.12-02-00430.1992.Peer-Reviewed Original ResearchConceptsRat optic nerveCompound action potentialAnoxic injuryOptic nerveWhite matterAction potentialsCentral white matter tractsWhite matter injuryCNS white matterMembrane depolarizationAnoxia/ischemiaWhite matter tractsCNS protectionAnoxic insultMyelinated tractsChannel blockersExchanger blockerIrreversible injuryExtracellular Ca2Mammalian CNSNerveInjuryMore injuriesBlockersFunctional integrity
1984
Impulse conduction in inhomogeneous axons: Effects of variation in voltage-sensitive ionic conductances on invasion of demyelinated axon segments and preterminal fibers
Waxman S, Wood S. Impulse conduction in inhomogeneous axons: Effects of variation in voltage-sensitive ionic conductances on invasion of demyelinated axon segments and preterminal fibers. Brain Research 1984, 294: 111-122. PMID: 6697227, DOI: 10.1016/0006-8993(84)91314-3.Peer-Reviewed Original Research
1982
Membranes, Myelin, and the Pathophysiology of Multiple Sclerosis
Waxman S. Membranes, Myelin, and the Pathophysiology of Multiple Sclerosis. New England Journal Of Medicine 1982, 306: 1529-1533. PMID: 7043271, DOI: 10.1056/nejm198206243062505.Peer-Reviewed Original ResearchConduction of trains of impulses in uniform myelinated fibers: Computed dependence on stimulus frequency
Wood S, Waxman S, Kocsis J. Conduction of trains of impulses in uniform myelinated fibers: Computed dependence on stimulus frequency. Neuroscience 1982, 7: 423-430. PMID: 7078731, DOI: 10.1016/0306-4522(82)90276-7.Peer-Reviewed Original Research
1981
Impulse entrainment: Computer simulations and studies on the parallel fibers of the cerebellum
Kocsis J, Cummins K, Waxman S, Malenka R. Impulse entrainment: Computer simulations and studies on the parallel fibers of the cerebellum. Experimental Neurology 1981, 72: 628-637. PMID: 7238712, DOI: 10.1016/0014-4886(81)90011-x.Peer-Reviewed Original Research
1980
Determinants of conduction velocity in myelinated nerve fibers
Waxman S. Determinants of conduction velocity in myelinated nerve fibers. Muscle & Nerve 1980, 3: 141-150. PMID: 6245357, DOI: 10.1002/mus.880030207.Peer-Reviewed Original Research
1979
Dependence of refractory period measurements on conduction distance: A computer simulation analysis
Waxman S, Kocsis J, Brill M, Swadlow H. Dependence of refractory period measurements on conduction distance: A computer simulation analysis. Clinical Neurophysiology 1979, 47: 717-724. PMID: 91501, DOI: 10.1016/0013-4694(79)90299-2.Peer-Reviewed Original Research
1978
Conduction through demyelinated plaques in multiple sclerosis: computer simulations of facilitation by short internodes.
Waxman S, Brill M. Conduction through demyelinated plaques in multiple sclerosis: computer simulations of facilitation by short internodes. Journal Of Neurology Neurosurgery & Psychiatry 1978, 41: 408. PMID: 660202, PMCID: PMC493046, DOI: 10.1136/jnnp.41.5.408.Peer-Reviewed Original Research
1977
Conduction in Myelinated, Unmyelinated, and Demyelinated Fibers
Waxman S. Conduction in Myelinated, Unmyelinated, and Demyelinated Fibers. JAMA Neurology 1977, 34: 585-589. PMID: 907529, DOI: 10.1001/archneur.1977.00500220019003.Peer-Reviewed Original ResearchConduction velocity and spike configuration in myelinated fibres: computed dependence on internode distance.
Brill M, Waxman S, Moore J, Joyner R. Conduction velocity and spike configuration in myelinated fibres: computed dependence on internode distance. Journal Of Neurology Neurosurgery & Psychiatry 1977, 40: 769. PMID: 925697, PMCID: PMC492833, DOI: 10.1136/jnnp.40.8.769.Peer-Reviewed Original Research
1976
Probability of conduction deficit as related to fiber length in random-distribution models of peripheral neuropathies
Waxman S, Brill M, Geschwind N, Sabin T, Lettvin J. Probability of conduction deficit as related to fiber length in random-distribution models of peripheral neuropathies. Journal Of The Neurological Sciences 1976, 29: 39-53. PMID: 181541, DOI: 10.1016/0022-510x(76)90079-4.Peer-Reviewed Original ResearchMeSH KeywordsHumansMathematicsModels, NeurologicalNeural ConductionParesthesiaPeripheral Nervous System DiseasesProbabilityConceptsPeripheral neuropathyAxonal dysfunctionSensory deficitsDistal sensory deficitsNormal sensory conductionRapid clinical progressionConduction deficitsSensory conductionClinical progressionNerve fibersConduction blockNeuropathyDysfunctionMarked reductionProximodistal gradientPossible correlatesDeficitsSmall increaseParesthesiaeAbnormalitiesProgression
1975
Integrative Properties and Design Principles of Axons
Waxman S. Integrative Properties and Design Principles of Axons. International Review Of Neurobiology 1975, 18: 1-40. PMID: 1107245, DOI: 10.1016/s0074-7742(08)60032-x.Peer-Reviewed Original Research