2024
Exploring new perspectives in immunology
Medzhitov R, Iwasaki A. Exploring new perspectives in immunology. Cell 2024, 187: 2079-2094. PMID: 38670066, DOI: 10.1016/j.cell.2024.03.038.Peer-Reviewed Original Research
2002
Toll-Like Receptors and Their Ligands
Barton G, Medzhitov R. Toll-Like Receptors and Their Ligands. Current Topics In Microbiology And Immunology 2002, 270: 81-92. PMID: 12467245, DOI: 10.1007/978-3-642-59430-4_5.Peer-Reviewed Original Research
2001
Evolutionary perspective on innate immune recognition
Mushegian A, Medzhitov R. Evolutionary perspective on innate immune recognition. Journal Of Cell Biology 2001, 155: 705-710. PMID: 11724812, PMCID: PMC2150873, DOI: 10.1083/jcb.200107040.Peer-Reviewed Original Research
2000
The Toll receptor family and microbial recognition
Medzhitov R, Janeway C. The Toll receptor family and microbial recognition. Trends In Microbiology 2000, 8: 452-456. PMID: 11044679, DOI: 10.1016/s0966-842x(00)01845-x.Peer-Reviewed Original ResearchViral interference with IL-1 and Toll signaling
Janeway C, Medzhitov R. Viral interference with IL-1 and Toll signaling. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 10682-10683. PMID: 11005852, PMCID: PMC34044, DOI: 10.1073/pnas.97.20.10682.Peer-Reviewed Original ResearchInnate immune recognition: mechanisms and pathways
Medzhitov R, Janeway C. Innate immune recognition: mechanisms and pathways. Immunological Reviews 2000, 173: 89-97. PMID: 10719670, DOI: 10.1034/j.1600-065x.2000.917309.x.Peer-Reviewed Original ResearchConceptsPattern recognition receptorsInnate immune systemMost multicellular organismsRecognition receptorsMulticellular organismsHost defenseInducible responsesImmune response genesResponse genesPathogen recognitionImmune systemMolecular patternsInfectious microbesAncient formPathwayReceptorsDefenseGenesMicrobesOrganismsMicroorganismsLarge groupPathogensExpressionPatterns
1999
Innate immunity: Lipoproteins take their Toll on the host
Janeway C, Medzhitov R. Innate immunity: Lipoproteins take their Toll on the host. Current Biology 1999, 9: r879-r882. PMID: 10607553, DOI: 10.1016/s0960-9822(00)80073-1.Peer-Reviewed Original ResearchThe Toll-receptor family and control of innate immunity
Kopp E, Medzhitov R. The Toll-receptor family and control of innate immunity. Current Opinion In Immunology 1999, 11: 13-18. PMID: 10047546, DOI: 10.1016/s0952-7915(99)80003-x.Peer-Reviewed Original ResearchConceptsInducible immune response genesToll receptor familyToll receptorTransduction pathwaysImmune response genesHost defense systemInnate immune recognitionMicrobial pathogensGermline-encoded receptorsNuclear factor-kappaBMolecular patternsDefense systemInnate immunityFactor-kappaBImmune recognitionPathwayReceptorsInsectsMammalsGenesPlantsPathogensExpressionKappaBFamily
1998
An ancient system of host defense
Medzhitov R, Janeway C. An ancient system of host defense. Current Opinion In Immunology 1998, 10: 12-15. PMID: 9523104, DOI: 10.1016/s0952-7915(98)80024-1.Peer-Reviewed Original ResearchSelf-defense: The fruit fly style
Medzhitov R, Janeway C. Self-defense: The fruit fly style. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 429-430. PMID: 9435208, PMCID: PMC33794, DOI: 10.1073/pnas.95.2.429.Peer-Reviewed Original Research
1997
Innate Immunity: The Virtues of a Nonclonal System of Recognition
Medzhitov R, Janeway C. Innate Immunity: The Virtues of a Nonclonal System of Recognition. Cell 1997, 91: 295-298. PMID: 9363937, DOI: 10.1016/s0092-8674(00)80412-2.Peer-Reviewed Original ResearchInnate immunity: impact on the adaptive immune response
Medzhitov R, Janeway C. Innate immunity: impact on the adaptive immune response. Current Opinion In Immunology 1997, 9: 4-9. PMID: 9039775, DOI: 10.1016/s0952-7915(97)80152-5.Peer-Reviewed Original ResearchMeSH KeywordsImmunity, Innate