2018
A liquid phase of synapsin and lipid vesicles
Milovanovic D, Wu Y, Bian X, De Camilli P. A liquid phase of synapsin and lipid vesicles. Science 2018, 361: 604-607. PMID: 29976799, PMCID: PMC6191856, DOI: 10.1126/science.aat5671.Peer-Reviewed Original ResearchConceptsSynaptic vesiclesNeurotransmitter-containing synaptic vesiclesCalmodulin-dependent protein kinase IILipid vesiclesCalcium/calmodulin-dependent protein kinase IIProtein kinase IISmall lipid vesiclesKinase IILiquid-liquid phase separationSynapsinDistinct liquid phasesVesiclesTight clusterSynapsin 1Presynaptic sitesPhosphorylationExocytosis
2001
Glutamate regulates actin-based motility in axonal filopodia
Chang S, De Camilli P. Glutamate regulates actin-based motility in axonal filopodia. Nature Neuroscience 2001, 4: 787-793. PMID: 11477424, DOI: 10.1038/90489.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBridged Bicyclo Compounds, HeterocyclicCalciumCalcium ChannelsCell DifferentiationCell MovementCells, CulturedCentral Nervous SystemGlutamic AcidGreen Fluorescent ProteinsGrowth ConesHippocampusImmunohistochemistryLuminescent ProteinsNeuronal PlasticityPseudopodiaRatsReceptors, AMPAReceptors, N-Methyl-D-AspartateTau ProteinsThiazolesThiazolidinesConceptsAdult nervous systemGlutamate receptorsNervous systemAxonal filopodiaAMPA/kainate glutamate receptorsKainate glutamate receptorsEffects of glutamateIonotropic glutamate receptorsCNQX treatmentSynaptic vesicle clustersAxonal arborsAxonal branchesDendritic spinesExtracellular Ca2Neurotransmitter glutamateSynaptic formationSynaptic plasticityInhibitory effectGlutamateReceptorsVesicle clustersNMDASynaptogenesisSpine