2001
Association of Na+-H+ Exchanger Isoform NHE3 and Dipeptidyl Peptidase IV in the Renal Proximal Tubule*
Girardi A, Degray B, Nagy T, Biemesderfer D, Aronson P. Association of Na+-H+ Exchanger Isoform NHE3 and Dipeptidyl Peptidase IV in the Renal Proximal Tubule*. Journal Of Biological Chemistry 2001, 276: 46671-46677. PMID: 11590171, DOI: 10.1074/jbc.m106897200.Peer-Reviewed Original ResearchConceptsApical membraneExchanger Isoform NHE3Dipeptidyl peptidase IVN-terminal sequencingProtein complexesDPPIV enzyme activityRenal microvillus membrane vesiclesMicrovillar fractionMembrane populationsMembrane vesiclesPeptidase IVWestern blot analysisMicrovillus membrane vesiclesNHE3 surface expressionBrush borderImmunoelectron microscopyRabbit renal brush borderBlot analysisProteinEnzyme activitySurface expressionMicrovillus membraneNHE3Different poolsImmunoaffinity chromatography
1991
High affinity binding of amiloride analogs at an internal site in renal microvillus membrane vesicles
Desir GV, Cragoe EJ, Aronson PS. High affinity binding of amiloride analogs at an internal site in renal microvillus membrane vesicles. Journal Of Biological Chemistry 1991, 266: 2267-2271. PMID: 1846621, DOI: 10.1016/s0021-9258(18)52238-9.Peer-Reviewed Original ResearchConceptsMembrane vesiclesMicrovillus membrane vesiclesRenal microvillus membrane vesiclesSimilar rank order potencyBinding sitesInternal sitesHigh-affinity inhibitorsMembrane localizationInternal binding siteAmiloride analoguesPlasma membraneRank order potencyHigh-affinity bindingAffinity inhibitorsHigh affinity-binding siteVesiclesBasolateral membrane vesiclesOrder potency
1984
Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles
Seifter JL, Knickelbein R, Aronson PS. Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles. American Journal Of Physiology 1984, 247: f753-f759. PMID: 6093589, DOI: 10.1152/ajprenal.1984.247.5.f753.Peer-Reviewed Original Research
1983
Specificity and modes of the anion exchanger in dog renal microvillus membranes
Guggino SE, Martin GJ, Aronson PS. Specificity and modes of the anion exchanger in dog renal microvillus membranes. American Journal Of Physiology 1983, 244: f612-f621. PMID: 6859253, DOI: 10.1152/ajprenal.1983.244.6.f612.Peer-Reviewed Original ResearchUrate transport via anion exchange in dog renal microvillus membrane vesicles
Kahn AM, Aronson PS. Urate transport via anion exchange in dog renal microvillus membrane vesicles. American Journal Of Physiology 1983, 244: f56-f63. PMID: 6849384, DOI: 10.1152/ajprenal.1983.244.1.f56.Peer-Reviewed Original ResearchConceptsDose-response curveP-aminohippurateUrate transportRenal microvillus membrane vesiclesUptake of PAHDog renal cortexMicrovillus membrane vesiclesAnion reabsorptionRenal cortexProximal tubulesTransport of urateUrateBrush border membrane vesiclesMembrane vesiclesUrate uptakePAH uptakeExternal ClPresent studyBorder membrane vesicles
1982
Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles
Aronson P, Nee J, Suhm M. Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles. Nature 1982, 299: 161-163. PMID: 7110335, DOI: 10.1038/299161a0.Peer-Reviewed Original ResearchConceptsRenal proximal tubular cellsProximal tubular cellsRenal microvillus membrane vesiclesIntracellular acid loadRegulation of intracellularMicrovillus membrane vesiclesTubular cellsDiuretic drugsDetermination of the coupling ratio for Na+-H+ exchange in renal microvillus membrane vesicles
Kinsella J, Aronson P. Determination of the coupling ratio for Na+-H+ exchange in renal microvillus membrane vesicles. Biochimica Et Biophysica Acta 1982, 689: 161-164. PMID: 7104347, DOI: 10.1016/0005-2736(82)90200-0.Peer-Reviewed Original ResearchGlucose and alanine inhibition of phosphate transport in renal microvillus membrane vesicles
Barrett PQ, Aronson PS. Glucose and alanine inhibition of phosphate transport in renal microvillus membrane vesicles. American Journal Of Physiology 1982, 242: f126-f131. PMID: 7065130, DOI: 10.1152/ajprenal.1982.242.2.f126.Peer-Reviewed Original ResearchConceptsInhibitory interactionsRenal cortexRabbit renal cortexProximal tubulesGlucose uptakeIntact proximal tubulesAlanine inhibitionRenal microvillus membrane vesiclesBrush border membrane vesicles
1981
Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles
Kinsella JL, Aronson PS. Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles. American Journal Of Physiology 1981, 241: f374-f379. PMID: 7315961, DOI: 10.1152/ajprenal.1981.241.4.f374.Peer-Reviewed Original ResearchUse of ionophores to study Na+ transport pathways in renal microvillus membrane vesicles.
Aronson PS, Kinsella JL. Use of ionophores to study Na+ transport pathways in renal microvillus membrane vesicles. The FASEB Journal 1981, 40: 2213-7. PMID: 6263713.Commentaries, Editorials and LettersConceptsMembrane vesiclesRenal microvillus membrane vesiclesMicrovillus membrane vesiclesUse of ionophoresPlasma membrane vesiclesTransport pathwaysMembrane potential